2-Chloro-n-(4-ethyl-5-methyl-1,3-thiazol-2-yl)acetamide CAS 878437-08-2
| CAS No. | 878437-08-2 |
| Molecular Formula | C8H11ClN2OS |
| Molecular Weight | 218.70 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Chloro-n-(4-ethyl-5-methyl-1,3-thiazol-2-yl)acetamide.
2-Chloro-n-(4-ethyl-5-methyl-1,3-thiazol-2-yl)acetamide (CAS 878437-08-2), molecular formula C8H11ClN2OS and molecular weight 218.70 g/mol, is a CATO reference standard with documented purity and traceability.
2-Chloro-n-(4-ethyl-5-methyl-1,3-thiazol-2-yl)acetamide (C8H11ClN2OS) contains a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H11ClN2OS |
| Molecular Weight | 218.70 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
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Recommended Standards
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- 1-(2-(1H-indol-3-yl)ethyl)-3-(4-cyanophenyl)thiourea (CAS 1023556-71-9)
- 1-(3-Chlorophenyl)-4,4-dimethylpentan-3-one (CAS 1099621-45-0)
- 5-[(3-chlorophenyl)methyl]-1,3-thiazol-2-amine (CAS 313960-06-4)
- 5-(Pyridin-4-yl)-1H-benzo[d]imidazole (CAS 82718-15-8)
- 3-Amino-N-(2-methoxyphenyl)-N-methylpropanamide (CAS 1018656-64-8)
- Dyclonine Impurity 38 (CAS CATO-C4X-188138)
- Neuropeptide Y (22-36) (CAS 119019-65-7)
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