3-(Morpholine-4-sulfonyl)thiophene-2-carboxylic acid CAS 878466-29-6
| CAS No. | 878466-29-6 |
| Molecular Formula | C9H11NO5S2 |
| Molecular Weight | 277.32 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
3-(Morpholine-4-sulfonyl)thiophene-2-carboxylic acid (CAS 878466-29-6) is a high-purity analytical reference standard with the molecular formula C9H11NO5S2 and a molecular weight of 277.32 g/mol.
The molecular framework of 3-(Morpholine-4-sulfonyl)thiophene-2-carboxylic acid (C9H11NO5S2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H11NO5S2 |
| Molecular Weight | 277.32 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 2 |
Related Morpholine Standards
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Recommended Standards
- 3-(5-Phenyl-1,3,4-oxadiazol-2-yl)-2-thioxothiazolidin-4-one (CAS 62329-46-8)
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- 3-(4-Methoxyphenyl)-4,5-dihydronaphtho[1,2-c]isoxazole (CAS 24097-25-4)
- 3,5-Bis(methylsulfonyl)benzamide (CAS 849924-85-2)
- (3,6-Dimethoxy-2-nitrophenyl)methanol (CAS 773869-81-1)
- 2-Bromo-1-(6-methylthiazolo[3,2-b][1,2,4]triazol-5-yl)ethanone hydrobromide (CAS 187597-19-9)
- 5-(4-Bromophenyl)-3-methyl-5-oxopentanoic acid (CAS 1343735-62-5)
- 3-Methyl-3-(3-(trifluoromethyl)phenyl)butanenitrile hydrochloride (CAS 959139-62-9)
- 1-(2-Methoxy-4-(trifluoromethoxy)phenyl)ethan-1-one (CAS 886500-08-9)
- 2-Methyl-1-oxo-1,2-dihydroisoquinoline-4-carbaldehyde (CAS 31588-53-1)
- 6-Methoxy-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(trifluoromethyl)pyridine (CAS 2813245-34-8)
- 2-Methyl-1-((3-(trifluoromethyl)pyridin-2-yl)oxy)propan-2-amine (CAS 1340143-02-3)
- N-(2-Aminoethyl)-2-chlorobenzamide (CAS 65389-77-7)
- (9-D-Asp) Semaglutide X Sodium salt (CAS CATO-CPTD788617)
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