Edaravone Impurity 29 CAS 881-05-0
| CAS No. | 881-05-0 |
| Molecular Formula | C10H8N2O2 |
| Molecular Weight | 188.18 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Edaravone Impurity 29 (CAS 881-05-0) is a certified pharmaceutical impurity reference standard with the molecular formula C10H8N2O2 and a molecular weight of 188.18 g/mol.
The molecular framework of Edaravone Impurity 29 (C10H8N2O2) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H8N2O2 |
| Molecular Weight | 188.18 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Nitrogen Atoms | 2 |
Related Edaravone Standards
- Edaravone Impurity 15 (CAS 27349-35-5)
- Edaravone Impurity 02 (CAS 122395-42-0)
- Edaravone Impurity 21 (CAS 5393-61-3)
- Edaravone Impurity 16 (CAS CATO-C4X-106216)
- Edaravone Impurity 10 (CAS 710307-89-4)
- Edaravone Impurity 11 (CAS CATO-C4X-106211)
- Edaravone Impurity 17 (CAS CATO-C4X-106217)
- Edaravone-d5 (CAS 1228765-67-0)
Recommended Standards
- Salmeterol Impurity 13 (CAS 86-48-6)
- Palbociclib Impurity 44 (CAS CATO-C4X-112544)
- 4,5-dimethoxyphthalonitrile (CAS 88946-67-2)
- Amoxicillin EP Impurity F (CAS 126247-63-0)
- Capecitabine Impurity 20 (CAS 2265218-64-0)
- Nebivolol Impurity 10 (CAS CATO-C4X-196810)
- Urapidil Impurity 19 (CAS 2287518-97-0)
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