Methyl 3-chlorothiophene-2-carboxylate CAS 88105-17-3
| CAS No. | 88105-17-3 |
| Molecular Formula | C6H5ClO2S |
| Molecular Weight | 176.62 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Methyl 3-chlorothiophene-2-carboxylate (C6H5ClO2S) contains a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Methyl 3-chlorothiophene-2-carboxylate (CAS 88105-17-3), molecular formula C6H5ClO2S and molecular weight 176.62 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Methyl 3-chlorothiophene-2-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H5ClO2S |
| Molecular Weight | 176.62 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1982 |
| Halogen Content | Cl-containing |
| Sulfur Atoms | 1 |
Related Methyl Standards
- 4-Chlorothiophene-2-carbohydrazide (CAS 1263212-33-4)
- 3-Chlorothiophene-2-carbohydrazide (CAS 478483-31-7)
- 5-Chlorothiophene-2-carbohydrazide (CAS 351983-31-8)
- Methyl 2-chlorothiophene-3-carboxylate (CAS 76360-42-4)
- Methyl 4-chlorothiophene-3-carboxylate (CAS 88770-14-3)
- 5-Chlorothiophene-2-carbothioamide (CAS 85347-12-2)
- 5-Chlorothiophene-2,4-dicarbaldehyde (CAS 65762-93-8)
- methyl 4-chlorothiophene-2-carboxylate (CAS 88105-19-5)
Recommended Standards
- 6-Chloro-4-hydroxy-2-(methylthio)pyrimidine (CAS 6632-63-9)
- N-(4-chlorothiazol-2-yl)acetamide (CAS 89283-43-2)
- 4-Ethyl-[1,2,3]thiadiazole-5-carbonyl chloride 889939-72-4 (CAS 889939-72-4)
- 5-Chloro-4-methylthiophene-2-carboxylic acid (CAS 74598-03-1)
- Bleomycin Sulfate (A mixture of bleomycin sulfate salts) (CAS 9041-93-4)
- (2-Methoxy-3-methylphenyl)methanol (CAS 74090-48-5)
- {1-[2-(Trifluoromethyl)benzyl]cyclobutyl}methanamine (CAS 1439900-15-8)
- (R)-2-((R)-6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinolin-1-yl)propan-1-ol (CAS 1260590-63-3)
- (2-Benzylbutyl)amine (CAS 1017145-79-7)
- (4-METHYLPIPERAZIN-1-YL)(P-TOLYL)METHANONE (CAS 219989-25-0)
- Methyl 2-amino-3-(tetrahydro-2h-pyran-2-yl)propanoate (CAS 1339645-42-9)
- 5-Methyl-5,8-diazaspiro[3.5]nonan-6-one (CAS 2102298-16-6)
- (1-benzylazetidin-2-yl)methanol (CAS 31247-34-4)
- Semaglutide impurity 237 (CAS CATO-C4X-2226237)
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