3-(4-Fluoro-3-methylphenyl)propanoic acid CAS 881189-64-6
| CAS No. | 881189-64-6 |
| Molecular Formula | C10H11FO2 |
| Molecular Weight | 182.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 3-(4-Fluoro-3-methylphenyl)propanoic acid (C10H11FO2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
3-(4-Fluoro-3-methylphenyl)propanoic acid (CAS 881189-64-6) is a high-purity analytical reference standard with the molecular formula C10H11FO2 and a molecular weight of 182.19 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-(4-Fluoro-3-methylphenyl)propanoic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H11FO2 |
| Molecular Weight | 182.19 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
Related Fluoro Standards
- 2-(4-Fluoro-3,5-dimethylphenyl)acetic acid (CAS 1000544-58-0)
- 1-(5-Fluoro-2-methoxyphenyl)propan-2-one (CAS 1017082-10-8)
- 3-(3-Fluoro-5-methylphenyl)propanoic acid (CAS 1017779-56-4)
- 3-Fluoro-4-(propan-2-yloxy)benzaldehyde (CAS 1021231-72-0)
- 3-(3-fluoro-4-methoxyphenyl)propanal (CAS 1036396-31-2)
- 3-Fluoro-2-isopropoxybenzaldehyde (CAS 1037092-98-0)
- Ethyl 3-Fluoro-2-methylbenzoate (CAS 114312-57-1)
- 2-(3-Fluoro-4-methoxyphenyl)-2-methyloxirane (CAS 1189785-35-0)
Recommended Standards
- 3-(3-Fluorophenyl)-2-methylpropanoic acid (CAS 41201-57-4)
- 3-(4-Fluorophenoxy)butan-2-one (CAS 30343-25-0)
- 3-(3-fluorophenoxy)-2-butanone (CAS 306979-64-6)
- 3-(4-Fluorophenyl)-2-methylpropanoic acid (CAS 22138-73-4)
- 2-((4-Fluorophenyl)amino)-2-methylpropanoic acid (CAS 725234-46-8)
- 5-(4-(Methylsulfonyl)benzyl)-1,3,4-oxadiazol-2-amine (CAS 1257553-09-5)
- (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)(methyl)amino)-5-((tert-butoxycarbonyl)amino)pentanoic acid (CAS 1793105-28-8)
- 2-amino-6-nitrobenzene-1-sulfonamide (CAS 1261676-63-4)
- 2-(4-Methoxyphenoxy)-5-methylaniline (CAS 17419-03-3)
- (4-benzyl-5-methylmorpholin-2-yl)methanol (CAS 1536090-77-3)
- 2-Isopropylphenyl Isothiocyanate (CAS 36176-31-5)
- 2-Amino-N-(2-((2-chlorobenzyl)amino)-2-oxoethyl)acetamide hydrochloride (CAS 1830910-26-3)
- 6-Bromo-3-methyl-4-nitro-1H-indole (CAS 374633-30-4)
- Semaglutide impurity 215 (CAS CATO-C4X-2226215)
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