Chloromethyl-(2-chlorophenoxy)dimethylsilane CAS 88127-54-2
| CAS No. | 88127-54-2 |
| Molecular Formula | C9H12Cl2OSi |
| Molecular Weight | 235.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Chloromethyl-(2-chlorophenoxy)dimethylsilane is closely related to a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies Chloromethyl-(2-chlorophenoxy)dimethylsilane (CAS 88127-54-2), a certified reference material (molecular formula C9H12Cl2OSi, MW 235.18 g/mol) for analytical method development and quality control.
The molecular framework of Chloromethyl-(2-chlorophenoxy)dimethylsilane (C9H12Cl2OSi) is characterized by a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Chloromethyl-(2-chlorophenoxy)dimethylsilane meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H12Cl2OSi |
| Molecular Weight | 235.18 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1982 |
| Halogen Content | Cl-containing |
Related Chloromethyl Standards
- Chloromethyl-(4-chlorophenoxy)dimethylsilane (CAS 203785-59-5)
- 2,6-Bis(chloromethyl)-1,4-dimethoxybenzene (CAS 1379163-23-1)
- 1,2-bis(chloromethyl)-4,5-dimethoxybenzene (CAS 1134-52-7)
- 3-(Chloromethyl)-5-(3-chlorothiophen-2-yl)-1,2,4-oxadiazole (CAS 1509882-79-4)
- 5,5'-Bis(chloromethyl)-3,3'-bi(1,2,4-oxadiazole) (CAS 3980-25-4)
- 2,4,6-Tris(chloromethyl)-1,3,5-trioxane (CAS 1129-52-8)
- 2-{[4-(chloromethyl)-1,3-thiazol-2-yl]methyl}pyridine (CAS 1094365-06-6)
- 6-(chloromethyl)-N-ethyl-N-(2-methoxyethyl)pyridin-2-amine (CAS 1248987-59-8)
Recommended Standards
- 4-((Trifluoromethyl)sulfonyl)benzonitrile (CAS 312-21-0)
- 2,2,6,6-Tetrafluoro-4-phenylmorpholine (CAS 65472-14-2)
- Methyl 4-cyano-5-(trifluoromethyl)thiophene-2-carboxylate (CAS 2168855-19-2)
- 2,2,2-Trifluoro-N-(4-fluorophenethyl)acetamide (CAS 912846-63-0)
- 2,4-Di-tert-butyl-6-chloropyrimidine (CAS 69050-89-1)
- (2-Fluoro-5-isopropoxyphenyl)methanol (CAS 1823942-53-5)
- 5-amino-3-(2-hydroxyethoxy)-1H-pyrazole-4-carbonitrile (CAS 117889-76-6)
- 5-Ethyl-1-(3-fluorophenyl)-1H-1,2,3-triazole-4-carboxylic acid (CAS 1094311-25-7)
- 3-Aminoazetidine-3-carbonitrile (CAS 1531313-58-2)
- Furo[2,3-c]pyridine-7-carbaldehyde (CAS 193750-93-5)
- (R)-2-Hydroxy-3-(4-hydroxyphenyl)propanoic Acid (CAS 89919-57-3)
- 3-([1,1'-Biphenyl]-4-yl)-2-aminopropanoic acid hydrochloride (CAS 63024-23-7)
- 3-(3-Nitrophenyl)-1H-1,2,4-triazol-5-amine (CAS 59301-20-1)
- Semaglutide Impurity 188 (CAS CATO-C4X-2226188)
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