2-(3,5-Dichlorobenzo[b]thiophen-2-yl)-5-phenyl-1,3,4-oxadiazole CAS 881384-49-2
| CAS No. | 881384-49-2 |
| Molecular Formula | C16H8Cl2N2OS |
| Molecular Weight | 347.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 2-(3,5-Dichlorobenzo[b]thiophen-2-yl)-5-phenyl-1,3,4-oxadiazole (C16H8Cl2N2OS) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
CATO supplies 2-(3,5-Dichlorobenzo[b]thiophen-2-yl)-5-phenyl-1,3,4-oxadiazole (CAS 881384-49-2), a certified reference material (molecular formula C16H8Cl2N2OS, MW 347.22 g/mol) for analytical method development and quality control.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H8Cl2N2OS |
| Molecular Weight | 347.22 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Dichlorobenzo Standards
- 3-(2-(4,7-Dichlorobenzo[d]oxazol-2-yl)ethyl)-5-ethyl-6-methylpyridin-2(1H)-one (CAS 135560-41-7)
- 3-(((4,7-Dichlorobenzo[d]oxazol-2-yl)methyl)amino)-5-ethyl-6-methylpyridin-2(1H)-one (CAS 135525-78-9)
- 2-(2-(5,7-Dichlorobenzo[d]oxazol-2-yl)ethyl)isoindoline-1,3-dione (CAS 1071369-46-4)
- (3,6-Dichlorobenzo[b]thiophen-2-yl)(3,4-dihydroquinolin-1(2H)-yl)methanone (CAS 332156-29-3)
- N-(4,5-Dichlorobenzo[d]thiazol-2-yl)-3-methylisoxazole-5-carboxamide (CAS 946286-95-9)
- N-(4,5-Dichlorobenzo[d]thiazol-2-yl)-1-methyl-1H-pyrazole-5-carboxamide (CAS 1170084-48-6)
- 3-(5,6-Dichlorobenzo[d]thiazol-2-yl)-N,N-dimethylpyridin-2-amine (CAS 400075-95-8)
- (3,6-Dichlorobenzo[b]thiophen-2-yl)(piperazin-1-yl)methanone (CAS 522597-21-3)
Recommended Standards
- 2'-Deoxyguanosine-5'-monophosphate (CAS 902-04-5)
- Ethyl 2-((5-(2,6-dichloropyridin-4-yl)-4-methyl-4H-1,2,4-triazol-3-yl)thio)acetate (CAS 680216-57-3)
- 2-(4-(2-(4-Bromo-2-fluorophenoxy)ethyl)piperazin-1-yl)ethanol (CAS 1704081-70-8)
- IMidazo[2,1-b]benzothiazole-3-carboxaldehyde, 2-(3,4-dichlorophenyl)- (CAS 901924-70-7)
- 6-Iodopravadoline (CAS 164178-33-0)
- Methyl 4-chloro-2-phenylpyrimidine-5-carboxylate (CAS 887580-16-7)
- tert-butyl (3aS,6aR)-2,2-dioxo-4,5,6,6a-tetrahydro-3aH-cyclopenta[d]oxathiazole-3-carboxylate (CAS 2145122-45-6)
- (2,3,5,6-Tetramethyl-1,4-phenylene)dimethanol (CAS 7522-62-5)
- 1-(4-Isobutoxy-2-methylphenyl)ethan-1-one (CAS 717915-97-4)
- 1,5-Bis-(4-methoxyphenyl)-3-pentadienone (CAS 2051-07-2)
- (5S)-N-cyclopropyl-1-azabicyclo[3.3.1]Nonan-3-amine (CAS 1423043-72-4)
- N-(4-Ethoxybenzyl)-2-isopropoxyaniline (CAS 1040683-17-7)
- 3-iodobicyclo[1.1.1]pentan-1-amine (CAS 351882-60-5)
- Semaglutide impurity 229 (CAS CATO-C4X-2226229)
Why CATO?
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