6-(4-Chlorophenyl)-3-isopropylisoxazolo[5,4-b]pyridine-4-carboxylic acid CAS 881443-07-8

Purity 97%+In StockPharmaceutical Standards
CAS No.881443-07-8
Molecular FormulaC16H13ClN2O3
Molecular Weight316.74 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

6-(4-Chlorophenyl)-3-isopropylisoxazolo[5,4-b]pyridine-4-carboxylic acid CAS 881443-07-8 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 316.74 g/mol gives 6-(4-Chlorophenyl)-3-isopropylisoxazolo[5,4-b]pyridine-4-carboxylic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

6-(4-Chlorophenyl)-3-isopropylisoxazolo[5,4-b]pyridine-4-carboxylic acid (CAS 881443-07-8) is a high-purity analytical reference standard with the molecular formula C16H13ClN2O3 and a molecular weight of 316.74 g/mol.

The molecular framework of 6-(4-Chlorophenyl)-3-isopropylisoxazolo[5,4-b]pyridine-4-carboxylic acid (C16H13ClN2O3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC16H13ClN2O3
Molecular Weight316.74 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)11.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1987
Halogen ContentCl-containing
Nitrogen Atoms2

Related Chlorophenyl Standards

Recommended Standards

Why CATO?