3',5'-O-[Tetrakis(1-methylethyl)-1,3-disiloxanediyl]guanosine CAS 88183-82-8
| CAS No. | 88183-82-8 |
| Molecular Formula | C22H39N5O6Si2 |
| Molecular Weight | 525.75 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3',5'-O-[Tetrakis(1-methylethyl)-1,3-disiloxanediyl]guanosine (CAS 88183-82-8) is a high-purity analytical reference standard with the molecular formula C22H39N5O6Si2 and a molecular weight of 525.75 g/mol.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, 3',5'-O-[Tetrakis(1-methylethyl)-1,3-disiloxanediyl]guanosine is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 525.75 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3',5'-O-[Tetrakis(1-methylethyl)-1,3-disiloxanediyl]guanosine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H39N5O6Si2 |
| Molecular Weight | 525.75 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1982 |
| Nitrogen Atoms | 5 |
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Recommended Standards
- Lefamulinum Impurity 7 (CAS CATO-C4X-30477)
- 3-5-O-(1-1-3-3-Tetraisopropyl-1-3-disiloxanediyl)guanosine (CAS 69304-44-5)
- Lefamulinum Impurity 1 (CAS CATO-C4X-30471)
- Ilmofosine (CAS 83519-04-4)
- (4-Bromophenyl)(5-hydroxybenzofuran-3-yl)methanone (CAS 723247-35-6)
- 5-Acetyl-2-methoxybenzonitrile (CAS 113016-89-0)
- 2,3,4,5-Tetrafluoro-6-(methylthio)benzaldehyde (CAS 2773501-85-0)
- Methyl 2-[5-fluoro-2-(trifluoromethyl)phenyl]acetate (CAS 1820703-52-3)
- (1R,5S,6S)-rel-8-methyl-8-azabicyclo[3.2.1]octan-6-ol (CAS 18700-21-5)
- Boc-β-(3-benzothienyl)-Ala-OH (CAS 154902-51-9)
- (3-Methylimidazo[2,1-b]thiazol-5-yl)methanol (CAS 174208-99-2)
- (3S,4R)-3-methoxypiperidin-4-ol hydrochloride (CAS 2173637-21-1)
- (5-(Tetrahydrofuran-2-yl)-4h-1,2,4-triazol-3-yl)methanamine (CAS 1490081-43-0)
- Semaglutide impurity 237 (CAS CATO-C4X-2226237)
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