3-((4-Chloro-3-nitrophenyl)amino)-1-(4-fluorophenyl)propan-1-one CAS 882748-61-0
| CAS No. | 882748-61-0 |
| Molecular Formula | C15H12ClFN2O3 |
| Molecular Weight | 322.72 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
3-((4-Chloro-3-nitrophenyl)amino)-1-(4-fluorophenyl)propan-1-one (CAS 882748-61-0) is a high-purity analytical reference standard with the molecular formula C15H12ClFN2O3 and a molecular weight of 322.72 g/mol.
The molecular framework of 3-((4-Chloro-3-nitrophenyl)amino)-1-(4-fluorophenyl)propan-1-one (C15H12ClFN2O3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), 3-((4-Chloro-3-nitrophenyl)amino)-1-(4-fluorophenyl)propan-1-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H12ClFN2O3 |
| Molecular Weight | 322.72 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
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Recommended Standards
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- 2-(((Tetrahydro-2h-pyran-4-yl)methyl)amino)propan-1-ol (CAS 1456496-72-2)
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- (S)-2-(2,2-Dimethyl-1,3-dioxolan-4-yl)acetamide (CAS 185996-33-2)
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