3-((4-Chlorophenyl)thio)-1-(4-fluoro-3-nitrophenyl)pyrrolidine-2,5-dione CAS 882749-44-2
| CAS No. | 882749-44-2 |
| Molecular Formula | C16H10ClFN2O4S |
| Molecular Weight | 380.78 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 3-((4-Chlorophenyl)thio)-1-(4-fluoro-3-nitrophenyl)pyrrolidine-2,5-dione is closely related to a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
3-((4-Chlorophenyl)thio)-1-(4-fluoro-3-nitrophenyl)pyrrolidine-2,5-dione (CAS 882749-44-2) is a high-purity analytical reference standard with the molecular formula C16H10ClFN2O4S and a molecular weight of 380.78 g/mol.
The molecular framework of 3-((4-Chlorophenyl)thio)-1-(4-fluoro-3-nitrophenyl)pyrrolidine-2,5-dione (C16H10ClFN2O4S) is characterized by a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 3-((4-Chlorophenyl)thio)-1-(4-fluoro-3-nitrophenyl)pyrrolidine-2,5-dione under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H10ClFN2O4S |
| Molecular Weight | 380.78 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Chlorophenyl Standards
- 4-((4-Chlorophenyl)thio)-1-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]quinoxaline (CAS 338420-44-3)
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- 4-[(2E)-3-(3-Chlorophenyl)prop-2-enoyl]phenyl 2-fluorobenzoate (CAS 298216-00-9)
- 1-(4-Chlorophenyl)-5-methyl-N-(3-(trifluoromethyl)phenyl)-1H-1,2,4-triazole-3-carboxamide (CAS 321431-21-4)
- 5-(4-Chlorophenyl)-1-(3-(trifluoromethyl)phenyl)-1H-pyrazole-3-carbohydrazide (CAS 955976-46-2)
- N-(4-chlorophenyl)-5-methyl-1-(3-(trifluoromethyl)phenyl)-1H-1,2,4-triazole-3-carboxamide (CAS 321431-38-3)
- 2-{[(2-chlorophenyl)methyl]sulfanyl}-5-[3-(trifluoromethyl)phenyl]pyrimidine (CAS 339101-97-2)
- 2-{[(3-chlorophenyl)methyl]sulfanyl}-5-[3-(trifluoromethyl)phenyl]pyrimidine (CAS 339101-99-4)
Recommended Standards
- 2-Chloro-1,5-dihydroxy-6-(4-methoxyphenyl)anthracene-9,10-dione (CAS 92753-68-9)
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- N-(2-benzoyl-4-chlorophenyl)-4-nitrobenzamide (CAS 157488-07-8)
- 7-Chloro-4-nitro-1-(p-tolyloxy)acridin-9(10H)-one (CAS 61290-20-8)
- n-Ethyl-N-(pyrrolidin-3-yl)but-2-enamide (CAS 1344883-24-4)
- DEET omega-Carboxylic Acid (CAS 72236-23-8)
- 5-(4-Chlorobenzyl)-4-methyl-4H-1,2,4-triazole-3-thiol (CAS 298686-92-7)
- Trichlophenidin (CAS 53720-80-2)
- 3-(tert-Butoxycarbonyl)-1,1-dimethyl-1,2,3,4-tetrahydrobenzo[d][1,3]azasiline-4-carboxylic acid (CAS 2222440-54-0)
- 4-(2,5-dimethyl-1-phenyl-1H-pyrrol-3-yl)-1,3-thiazol-2-amine hydrochloride (CAS 1052550-77-2)
- N-(1-cyanocyclopentyl)acetamide (CAS 5009-09-6)
- 6-Bromo-2-methoxynicotinonitrile (CAS 1256790-45-0)
- 2-[(4-ethyl-5-phenyl-4h-1,2,4-triazol-3-yl)sulfanyl]acetohydrazide (CAS 893726-25-5)
- Semaglutide impurity 273 (CAS CATO-C4X-2226273)
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