3-Trifluoromethyl-4-hydroxy-5-methoxy Methyl Benzoate CAS 883241-39-2
| CAS No. | 883241-39-2 |
| Molecular Formula | C10H9F3O4 |
| Molecular Weight | 250.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3-Trifluoromethyl-4-hydroxy-5-methoxy Methyl Benzoate (CAS 883241-39-2) is a high-purity analytical reference standard with the molecular formula C10H9F3O4 and a molecular weight of 250.17 g/mol.
The molecular framework of 3-Trifluoromethyl-4-hydroxy-5-methoxy Methyl Benzoate (C10H9F3O4) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H9F3O4 |
| Molecular Weight | 250.17 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
Related Trifluoromethyl Standards
- 2-(3-(Trifluoromethyl)-6,7-dihydropyrano[4,3-c]pyrazol-1(4H)-yl)acetic acid (CAS 1189583-13-8)
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- 3-Methyl-6-(trifluoromethyl)imidazo[2,1-b]thiazole-5-carboxylic acid (CAS 1368302-66-2)
- 2-Methyl-6-(trifluoromethyl)imidazo[2,1-b]thiazole-5-carboxylic acid (CAS 1369332-25-1)
- 5-((Trifluoromethyl)sulfonyl)-1H-benzo[d]imidazole (CAS 1417341-55-9)
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Recommended Standards
- 3,3,3-Trifluoro-2-hydroxy-2-(4-methoxyphenyl)propionic acid (CAS 502607-25-2)
- 4,4,4-trifluoro-2,3-dihydroxy-3-phenylbutanoic acid (CAS 1989671-67-1)
- 3-(4-(Trifluoromethoxy)phenoxy)propanoic acid (CAS 874774-55-7)
- 4,7-dichloroimidazo[1,5-a]quinoxaline (CAS 847900-55-4)
- 1-(Triphenylsilyl)ethanol (CAS 18666-82-5)
- 4-chlorobenzene-1-carboximidamide hydrochloride (CAS 14401-51-5)
- methyl N-(2-oxoethyl)-N-phenylcarbamate (CAS 288371-85-7)
- 1-(2-Chlorobenzyl)-3-methyl-1h-pyrazol-5-amine (CAS 3524-40-1)
- 4-[2-(3,4-dichlorophenyl)-2-oxoethoxy]-3-methoxybenzaldehyde (CAS 723333-45-7)
- 2-(4-(2-Methoxyphenyl)piperazin-1-yl)-9-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidine-3-carbaldehyde (CAS 496011-40-6)
- Tadalafil Impurity 84 (CAS CATO-C4X-108784)
- (S)-4-(Trifluoromethyl)-2,3-dihydro-1H-inden-1-amine hydrochloride (CAS 2514660-83-2)
- 2-(2-Bromophenoxy)-N,N-dimethylethan-1-amine (CAS 886851-37-2)
- Biotinyl-Neuropeptide Y (human, rat) trifluoroacetate salt (CAS 213779-13-6)
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