3-Chloro-7-(4-methylpiperazin-1-yl)quinoline-8-carbonitrile CAS 88347-10-8
| CAS No. | 88347-10-8 |
| Molecular Formula | C15H15ClN4 |
| Molecular Weight | 286.76 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-Chloro-7-(4-methylpiperazin-1-yl)quinoline-8-carbonitrile.
3-Chloro-7-(4-methylpiperazin-1-yl)quinoline-8-carbonitrile (CAS 88347-10-8) is a high-purity analytical reference standard with the molecular formula C15H15ClN4 and a molecular weight of 286.76 g/mol.
The molecular framework of 3-Chloro-7-(4-methylpiperazin-1-yl)quinoline-8-carbonitrile (C15H15ClN4) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C15H15ClN4 |
| Molecular Weight | 286.76 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1982 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
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- (2R,3S)-5-Ethoxy-5-(ethylthio)pentane-1,2,3-triol (CAS 115214-11-4)
- Semaglutide impurity 101 (CAS CATO-C4X-2226101)
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