N-Ethyl-2-(quinolin-8-yloxy)acetamide CAS 88349-77-3
| CAS No. | 88349-77-3 |
| Molecular Formula | C13H14N2O2 |
| Molecular Weight | 230.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 230.26 g/mol gives N-Ethyl-2-(quinolin-8-yloxy)acetamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
N-Ethyl-2-(quinolin-8-yloxy)acetamide (CAS 88349-77-3) is a high-purity analytical reference standard with the molecular formula C13H14N2O2 and a molecular weight of 230.26 g/mol.
The molecular framework of N-Ethyl-2-(quinolin-8-yloxy)acetamide (C13H14N2O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), N-Ethyl-2-(quinolin-8-yloxy)acetamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H14N2O2 |
| Molecular Weight | 230.26 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1982 |
| Nitrogen Atoms | 2 |
Recommended Standards
- N-ethyl-2-(2-methyl-1H-indol-3-yl)-2-oxoacetamide (CAS 478041-45-1)
- Propargyl-PEG3-methyl ester (CAS 2086689-09-8)
- N-Benzyl-N-(4-methyloxazol-2-yl)acetamide (CAS 57068-04-9)
- Propylthiouracil Impurity 3 (CAS 21633-79-4)
- 5-Chloro-7-(3-methoxyphenyl)quinolin-8-ol (CAS 648896-41-7)
- 5-((4-Chlorophenyl)thio)-N-(4-fluorophenyl)-1,3-dimethyl-1H-pyrazole-4-carboxamide (CAS 158712-49-3)
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- 1-[(4-methoxyphenyl)methyl]-3,5-dimethyl-1H-pyrazole-4-carbaldehyde (CAS 163814-56-0)
- (5-Chloro-3-(trifluoromethyl)pyridin-2-yl)methanamine (CAS 1393552-67-4)
- 1-(3,4-Dichlorophenyl)butan-1-one (CAS 6582-45-2)
- N-hydroxy-3-methoxybenzamide (CAS 31791-98-7)
- D-Pro37-Tirzepatide (CAS CATO-CPTD788902)
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