N-(tert-Butyloxy)carbonyl-L-thyroxine CAS 88404-22-2

Purity 97%+In StockPharmaceutical Standards
CAS No.88404-22-2
Molecular FormulaC20H19I4NO6
Molecular Weight876.99 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

N-(tert-Butyloxy)carbonyl-L-thyroxine CAS 88404-22-2 chemical structure

Description

The occurrence of N-(tert-Butyloxy)carbonyl-L-thyroxine is closely related to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, iodine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies N-(tert-Butyloxy)carbonyl-L-thyroxine (CAS 88404-22-2), a certified reference material (molecular formula C20H19I4NO6, MW 876.99 g/mol) for analytical method development and quality control.

The molecular framework of N-(tert-Butyloxy)carbonyl-L-thyroxine (C20H19I4NO6) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage, iodine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), N-(tert-Butyloxy)carbonyl-L-thyroxine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC20H19I4NO6
Molecular Weight876.99 g/mol
Purity97%+
StorageStore at room temperature, protect from light, keep sealed and dry
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)10.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1982
Halogen ContentI-containing
Nitrogen Atoms1

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