| CAS No. | 88404-22-2 |
| Molecular Formula | C20H19I4NO6 |
| Molecular Weight | 876.99 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
The occurrence of N-(tert-Butyloxy)carbonyl-L-thyroxine is closely related to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, iodine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies N-(tert-Butyloxy)carbonyl-L-thyroxine (CAS 88404-22-2), a certified reference material (molecular formula C20H19I4NO6, MW 876.99 g/mol) for analytical method development and quality control.
The molecular framework of N-(tert-Butyloxy)carbonyl-L-thyroxine (C20H19I4NO6) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage, iodine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), N-(tert-Butyloxy)carbonyl-L-thyroxine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
| Molecular Formula | C20H19I4NO6 |
| Molecular Weight | 876.99 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1982 |
| Halogen Content | I-containing |
| Nitrogen Atoms | 1 |