2-Chlorothiazolo[4,5-c]pyridine CAS 884860-63-3
| CAS No. | 884860-63-3 |
| Molecular Formula | C6H3ClN2S |
| Molecular Weight | 170.62 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
2-Chlorothiazolo[4,5-c]pyridine (CAS 884860-63-3) is a high-purity analytical reference standard with the molecular formula C6H3ClN2S and a molecular weight of 170.62 g/mol.
The molecular framework of 2-Chlorothiazolo[4,5-c]pyridine (C6H3ClN2S) is characterized by a nitrile group, sulfur-containing functionality, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H3ClN2S |
| Molecular Weight | 170.62 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Chlorothiazolo Standards
- 2-Chlorothiazolo[5,4-c]pyridine (CAS 1190927-31-1)
- 6-Chlorothiazolo[4,5-c]pyridine (CAS 1206982-73-1)
- 5-Chlorothiazolo[5,4-b]pyridine (CAS 1313726-12-3)
- 7-Chlorothiazolo[5,4-b]pyridine (CAS 1427501-90-3)
- 7-Chlorothiazolo[4,5-b]pyridine (CAS 1556129-57-7)
- 2-Chlorothiazolo[5,4-b]pyridine (CAS 91524-96-8)
- 4-Chlorothiazolo[4,5-c]pyridine (CAS 214045-74-6)
- 6-Chlorothiazolo[5,4-b]pyridine (CAS 886373-54-2)
Recommended Standards
- 2-Chloro-5-isothiocyanatopyridine (CAS 323588-81-4)
- 2-Chloro-3-isothiocyanatopyridine (CAS 50470-12-7)
- 3-Chloro-2-isothiocyanatopyridine (CAS 61737-23-3)
- 5-Chloro-4-mercaptonicotinonitrile (CAS 1706445-79-5)
- 3-Chloro-2-[4-(naphthalene-2-carbonyl)-1H-1,2,3-triazol-1-yl]-5-(trifluoromethyl)pyridine (CAS 478248-73-6)
- N,N-Dimethyl-3-(pyrrolidin-1-yl)aniline (CAS 677276-43-6)
- N,N-Dimethyl-9-(3-methylbenzyl)-9H-purin-6-amine (CAS 112089-17-5)
- 6-(2-Methoxyphenyl)-2-methylpyrimidin-4(3H)-one (CAS 56045-25-1)
- Tert-butyl ((4-(hydroxymethyl)bicyclo[2.2.1]Heptan-1-yl)methyl)carbamate (CAS 2108663-71-2)
- 3-Ethyl-3-methylpentan-1-ol (CAS 10524-71-7)
- 6-((1H-Pyrazol-1-yl)methyl)-4-methoxybenzo[d]isoxazol-3-amine (CAS 2568912-43-4)
- 4-Oxo-2-phenyl-4,5-dihydropyrazolo[1,5-a]pyrazine-3-carbaldehyde (CAS 1610377-19-9)
- (3-Amino-6-chloro-2-fluorophenyl)methanol (CAS 2386230-73-3)
- Endo-Gly4-Semaglutide (CAS CATO-C4X-222679)
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