1-(2-Chloro-1,3-thiazol-5-yl)ethanone CAS 885229-41-4

Description

Compared with other compounds in its class, the molecular weight of 161.61 g/mol gives 1-(2-Chloro-1,3-thiazol-5-yl)ethanone distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

1-(2-Chloro-1,3-thiazol-5-yl)ethanone (CAS 885229-41-4), molecular formula C5H4ClNOS and molecular weight 161.61 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 1-(2-Chloro-1,3-thiazol-5-yl)ethanone (C5H4ClNOS) is characterized by an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 1-(2-Chloro-1,3-thiazol-5-yl)ethanone under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

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