2-Bromo-1,4-bis(difluoromethoxy)benzene CAS 885266-93-3
| CAS No. | 885266-93-3 |
| Molecular Formula | C8H5BrF4O2 |
| Molecular Weight | 289.02 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Bromo-1,4-bis(difluoromethoxy)benzene.
2-Bromo-1,4-bis(difluoromethoxy)benzene (CAS 885266-93-3) is a high-purity analytical reference standard with the molecular formula C8H5BrF4O2 and a molecular weight of 289.02 g/mol.
Structurally, 2-Bromo-1,4-bis(difluoromethoxy)benzene (C8H5BrF4O2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/bromine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 289.02 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-Bromo-1,4-bis(difluoromethoxy)benzene meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H5BrF4O2 |
| Molecular Weight | 289.02 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Br-containing |
Related Bromo Standards
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Recommended Standards
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- 2-Chloro-N-(3,5-dichloropyridin-2-yl)propanamide (CAS 565172-40-9)
- (S)-1-((1R,3R,4R,5R)-4-(benzoyloxy)-5-methyl-2,6-dioxabicyclo[3.1.0]Hexan-3-yl)ethyl benzoate (CAS 1638744-21-4)
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- Ethyl 3-(4-benzylpiperidin-1-yl)propanoate (CAS 1099610-66-8)
- 352330-51-9 N',4-dihydroxy-3-methoxybenzene-1-carboximidamide NE54209 (CAS 352330-51-9)
- Peptide YY (13-36) (canine, mouse, porcine, rat) (CAS 86895-09-2)
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