6-Bromo-8-methoxy-2H-chromene-3-carboxylic acid methyl ester CAS 885271-18-1

Purity 97%+In StockPharmaceutical Standards
CAS No.885271-18-1
Molecular FormulaC12H11BrO4
Molecular Weight299.12 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

6-Bromo-8-methoxy-2H-chromene-3-carboxylic acid methyl ester CAS 885271-18-1 chemical structure

Description

6-Bromo-8-methoxy-2H-chromene-3-carboxylic acid methyl ester (CAS 885271-18-1) is a high-purity analytical reference standard with the molecular formula C12H11BrO4 and a molecular weight of 299.12 g/mol.

The molecular framework of 6-Bromo-8-methoxy-2H-chromene-3-carboxylic acid methyl ester (C12H11BrO4) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 6-Bromo-8-methoxy-2H-chromene-3-carboxylic acid methyl ester under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC12H11BrO4
Molecular Weight299.12 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)7.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1987
Halogen ContentBr-containing

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