8-Methoxy-chroman-3-carboxylic acid methyl ester CAS 885271-65-8
| CAS No. | 885271-65-8 |
| Molecular Formula | C12H14O4 |
| Molecular Weight | 222.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 222.24 g/mol gives 8-Methoxy-chroman-3-carboxylic acid methyl ester distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 8-Methoxy-chroman-3-carboxylic acid methyl ester (CAS 885271-65-8), a certified reference material (molecular formula C12H14O4, MW 222.24 g/mol) for analytical method development and quality control.
The molecular framework of 8-Methoxy-chroman-3-carboxylic acid methyl ester (C12H14O4) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H14O4 |
| Molecular Weight | 222.24 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
Related Methoxy Standards
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- 2-methoxy-1-[4-(oxiranylmethoxy)phenyl]ethanone (CAS 110458-44-1)
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Recommended Standards
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- AcBut (CAS 65623-82-7)
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- (2Z)-2-[4-(3-Fluoropropoxy)phenyl]-3-{[3-(trifluoromethyl)phenyl]amino}prop-2-enenitrile (CAS 478039-65-5)
- 4-Nitro-1-((3-(trifluoromethyl)phenoxy)methyl)-1H-pyrazole (CAS 1003993-37-0)
- 2-(6-Amino-4-bromo-5-(difluoromethyl)pyridin-2-yl)acetonitrile (CAS 1806806-66-5)
- 3-Ethoxypyridine 1-oxide (CAS 102074-24-8)
- 4,4’-Diamino-2,2’-bipyridyl (CAS 18511-69-8)
- 5-Hydroxy-4-(m-tolyl)isoquinolin-1(2H)-one (CAS 656234-19-4)
- n-((1,2,3-Thiadiazol-4-yl)methyl)-2-(methylthio)aniline (CAS 1154297-12-7)
- rac-(1R,6S)-bicyclo[4.1.0]heptan-2-one (CAS 196488-91-2)
- Des-Asp15-Tirzepatide (CAS CATO-CPTD788958)
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