4-Chloro-2-phenyl-5-(thiophen-2-yl)thieno[2,3-d]pyrimidine CAS 885524-09-4

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-Chloro-2-phenyl-5-(thiophen-2-yl)thieno[2,3-d]pyrimidine.

4-Chloro-2-phenyl-5-(thiophen-2-yl)thieno[2,3-d]pyrimidine (CAS 885524-09-4) is a high-purity analytical reference standard with the molecular formula C16H9ClN2S2 and a molecular weight of 328.84 g/mol.

Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine substitution, 4-Chloro-2-phenyl-5-(thiophen-2-yl)thieno[2,3-d]pyrimidine is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 328.84 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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