4-(2-Chloro-1,1,2-trifluoroethoxy)phenol CAS 88553-89-3
| CAS No. | 88553-89-3 |
| Molecular Formula | C8H6ClF3O2 |
| Molecular Weight | 226.58 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4-(2-Chloro-1,1,2-trifluoroethoxy)phenol is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
4-(2-Chloro-1,1,2-trifluoroethoxy)phenol (CAS 88553-89-3), molecular formula C8H6ClF3O2 and molecular weight 226.58 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system, 4-(2-Chloro-1,1,2-trifluoroethoxy)phenol is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 226.58 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 4-(2-Chloro-1,1,2-trifluoroethoxy)phenol under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H6ClF3O2 |
| Molecular Weight | 226.58 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1982 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- 1-Acetyl-4-chloro-3-methyl-5-(trifluoromethyl)-1H-pyrazole (CAS 1017793-54-2)
- 2-Chloro-4-ethoxy-6-(trifluoromethyl)pyrimidine (CAS 114963-95-0)
- 2-Chloro-4-(2,2,2-trifluoro-1-hydroxyethyl)phenol (CAS 1250225-28-5)
- 1-Chloro-2-methoxy-4-(trifluoromethoxy)benzene (CAS 1260893-33-1)
- 2-Chloro-1-methoxy-4-(trifluoromethoxy)benzene (CAS 1260893-38-6)
- 4-chloro-2-methoxy-1-(trifluoromethoxy)benzene (CAS 1261450-21-8)
- (2-Chloro-5-trifluoromethoxy-phenyl)-methanol (CAS 1261483-31-1)
- (4-Chloro-2-(trifluoromethoxy)phenyl)methanol (CAS 1261673-90-8)
Recommended Standards
- 3-Chloro-4-(trifluoromethoxy)benzyl Alcohol (CAS 56456-48-5)
- 4-Chloro-2-ethoxy-6-(trifluoromethyl)pyrimidine (CAS 932701-91-2)
- 2-Chloro-4-(2,2,2-trifluoroethoxy)phenol (CAS 444341-80-4)
- 4-Chloro-3-(trifluoromethoxy)benzyl Alcohol (CAS 886500-89-6)
- tert-Butyl ((2-(trifluoromethyl)pyrrolidin-2-yl)methyl)carbamate (CAS 2132400-31-6)
- N-Ethyl-N-methylundecan-1-amine (CAS 59570-02-4)
- (Z)-2-(3,4-dimethoxyphenyl)-3-phenylacrylonitrile (CAS 2958-55-6)
- N-(Prop-2-yn-1-yl)benzo[d][1,3]dioxole-5-carboxamide (CAS 1057940-55-2)
- 1-(5-(Chloromethyl)-2-hydroxyphenyl)ethanone (CAS 30787-43-0)
- 2-Amino-6-(6-fluoropyridin-2-yl)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carbonitrile (CAS 338413-86-8)
- Methyl 3-((tert-butoxycarbonyl)amino)-2-methylpropanoate (CAS 182486-16-4)
- 4,6,8-Trimethyl-N-(4,4,6-trimethyl-1,4-dihydropyrimidin-2-yl)quinazolin-2-amine (CAS 314039-40-2)
- H-DL-Leu-DL-Ala-OH (CAS 5060-46-8)
- Eosinophilotactic Peptide (CAS 61756-28-3)
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