1-(1-(4-Fluorophenyl)-1-phenylbut-3-yn-1-yl)-1H-imidazole CAS 88557-62-4

Purity 97%+In StockPharmaceutical Standards
CAS No.88557-62-4
Molecular FormulaC19H15FN2
Molecular Weight290.33 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

1-(1-(4-Fluorophenyl)-1-phenylbut-3-yn-1-yl)-1H-imidazole CAS 88557-62-4 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-(1-(4-Fluorophenyl)-1-phenylbut-3-yn-1-yl)-1H-imidazole.

1-(1-(4-Fluorophenyl)-1-phenylbut-3-yn-1-yl)-1H-imidazole (CAS 88557-62-4), molecular formula C19H15FN2 and molecular weight 290.33 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 1-(1-(4-Fluorophenyl)-1-phenylbut-3-yn-1-yl)-1H-imidazole (C19H15FN2) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 1-(1-(4-Fluorophenyl)-1-phenylbut-3-yn-1-yl)-1H-imidazole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC19H15FN2
Molecular Weight290.33 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)13.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1982
Halogen ContentF-containing
Nitrogen Atoms2

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