Fmoc-1-pyrrolidine-3-carboxylic acid CAS 885951-89-3
| CAS No. | 885951-89-3 |
| Molecular Formula | C20H19NO4 |
| Molecular Weight | 337.37 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Fmoc-1-pyrrolidine-3-carboxylic acid (C20H19NO4) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO supplies Fmoc-1-pyrrolidine-3-carboxylic acid (CAS 885951-89-3), a certified reference material (molecular formula C20H19NO4, MW 337.37 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Fmoc-1-pyrrolidine-3-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C20H19NO4 |
| Molecular Weight | 337.37 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 1 |
Related Fmoc Standards
- Fmoc-L-cyclopropylglycine (CAS 1212257-18-5)
- Fmoc-Cyclopropylglycine (CAS 1332765-55-5)
- N-Fmoc-N-methyl-1-amino-1-cyclopropanecarboxylic acid (CAS 1702888-95-6)
- (3S)-Fmoc-1-pyrrolidine-3-carboxylic acid (CAS 193693-66-2)
- Fmoc-1-amino-1-cyclobutane carboxylic acid (CAS 885951-77-9)
- Fmoc-Pro-OH (CAS 71989-31-6)
- Fmoc-D-Pro-OH (CAS 101555-62-8)
- Fmoc-α-allyl-D-Gly-OH (CAS 170642-28-1)
Recommended Standards
- ISAM 140 (CAS 932191-62-3)
- FA-Ala-Lys-OH (M-1350.0250) (CAS 76079-03-3)
- Kyotorphin (CAS 70904-56-2)
- Ethyl N-((4-fluorophenyl)sulfonyl)-N-phenylglycinate (CAS 3109-55-5)
- tert-Butyl (6-(trifluoromethyl)pyridin-3-yl)carbamate (CAS 325457-86-1)
- 3-Fluoro-4-(3-methylphenyl)benzoic acid (CAS 1261993-08-1)
- Famitinib (CAS 1044040-56-3)
- 5-Cyclopropyl-2-fluoropyridine (CAS 1034467-80-5)
- 9-Amino-8,9-dihydropyrido[1,2-a]indol-6(7H)-one (CAS 175022-99-8)
- (R)-2-(1-Pyrrolidinyl)butyric Acid (CAS 1932770-29-0)
- 1-(2,5-Dimethyl-1h-pyrrol-3-yl)-2-((4-methylthiazol-2-yl)thio)ethan-1-one (CAS 1152953-06-4)
- (E)-4-(3-(4-Isobutylphenyl)-3-oxoprop-1-en-1-yl)benzoic acid (CAS 2651958-56-2)
- Methyl 2-ethoxy-6-hydroxybenzoate (CAS 74292-71-0)
- Des-[Ser]8-Liraglutide (CAS CATO-C4X-199233)
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