6-[(2-Chlorophenyl)methoxy]-3,4-dihydro-2H-naphthalen-1-one CAS 88628-48-2
| CAS No. | 88628-48-2 |
| Molecular Formula | C17H15ClO2 |
| Molecular Weight | 286.75 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 6-[(2-Chlorophenyl)methoxy]-3,4-dihydro-2H-naphthalen-1-one is closely related to a steroid core, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
6-[(2-Chlorophenyl)methoxy]-3,4-dihydro-2H-naphthalen-1-one (CAS 88628-48-2) is a high-purity analytical reference standard with the molecular formula C17H15ClO2 and a molecular weight of 286.75 g/mol.
The molecular framework of 6-[(2-Chlorophenyl)methoxy]-3,4-dihydro-2H-naphthalen-1-one (C17H15ClO2) is characterized by a steroid core, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 6-[(2-Chlorophenyl)methoxy]-3,4-dihydro-2H-naphthalen-1-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C17H15ClO2 |
| Molecular Weight | 286.75 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1982 |
| Halogen Content | Cl-containing |
Related Chlorophenyl Standards
- (E)-5-(4-Chlorophenyl)-3-phenylpent-2-enoic Acid (CAS 1180676-33-8)
- (2E)-1-(2-Chlorophenyl)-3-(2-ethoxyphenyl)prop-2-en-1-one (CAS 1354941-60-8)
- (2E)-1-(3-Chlorophenyl)-3-(4-ethoxyphenyl)prop-2-en-1-one (CAS 1354941-96-0)
- (2E)-1-(3-Chlorophenyl)-3-(2-ethoxyphenyl)prop-2-en-1-one (CAS 1354942-23-6)
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- (2E)-1-(2-Chlorophenyl)-3-(4-ethoxyphenyl)prop-2-en-1-one (CAS 93330-19-9)
- (2E)-3-(2-Chlorophenyl)-1-(4-ethoxyphenyl)prop-2-en-1-one (CAS 358343-53-0)
Recommended Standards
- 5,5'-((4-Chlorophenyl)methylene)bis(2-methylfuran) (CAS 86694-53-3)
- 6-[(4-Chlorophenyl)methoxy]-3,4-dihydro-2H-naphthalen-1-one (CAS 88628-47-1)
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