2h-3,1-benzoxazine-8-carboxylic acid, 1,4-dihydro-2,4-dioxo-, methyl ester 3-isatoic anhydride carboxylic acid methyl ester 886362-85-2 Methyl 2,4-dioxo-2,4-dihydro-1H-benzo[d][1,3]oxazine-8-carboxylate methyl 1,4-dihydro-2,4-dioxo-2h-3,1-benzoxazine-8-carboxylate methyl 2,4-dioxo-1,4-dihydro-2h-3,1-benzoxazine-8-carboxylate ref dupl: 3-isatoic anhydride carboxylic acid methyl ester CAS 886362-85-2
| CAS No. | 886362-85-2 |
| Molecular Formula | C10H7NO5 |
| Molecular Weight | 221.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
2h-3,1-benzoxazine-8-carboxylic acid, 1,4-dihydro-2,4-dioxo-, methyl ester 3-isatoic anhydride carboxylic acid methyl ester 886362-85-2 Methyl 2,4-dioxo-2,4-dihydro-1H-benzo[d][1,3]oxazine-8-carboxylate methyl 1,4-dihydro-2,4-dioxo-2h-3,1-benzoxazine-8-carboxylate methyl 2,4-dioxo-1,4-dihydro-2h-3,1-benzoxazine-8-carboxylate ref dupl: 3-isatoic anhydride carboxylic acid methyl ester (CAS 886362-85-2), molecular formula C10H7NO5 and molecular weight 221.17 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2h-3,1-benzoxazine-8-carboxylic acid, 1,4-dihydro-2,4-dioxo-, methyl ester 3-isatoic anhydride carboxylic acid methyl ester 886362-85-2 Methyl 2,4-dioxo-2,4-dihydro-1H-benzo[d][1,3]oxazine-8-carboxylate methyl 1,4-dihydro-2,4-dioxo-2h-3,1-benzoxazine-8-carboxylate methyl 2,4-dioxo-1,4-dihydro-2h-3,1-benzoxazine-8-carboxylate ref dupl: 3-isatoic anhydride carboxylic acid methyl ester (C10H7NO5) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H7NO5 |
| Molecular Weight | 221.17 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 1 |
Related h Standards
- 2H-1,4-benzoxazine, 8-bromo-3,4-dihydro-2,2-dimethyl- (CAS 853683-76-8)
- 2H-1,4-Benzoxazine-7-sulfonyl chloride, 3,4-dihydro-3-oxo- (CAS 868962-24-7)
- 2H-1,4-Benzoxazine-3-acetonitrile, 7-fluoro-3,4-dihydro-, (3S)- (CAS 2883019-53-0)
- 1-ethyl-3,1-benzoxazine-2,4-dione (CAS 50332-68-8)
- 2H-1,4-Benzoxazine-3-methanol, 7-fluoro-3,4-dihydro-, (3S)- (CAS 2883019-47-2)
- 2H-1,4-Benzoxazine, 3,4-dihydro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)- (CAS 1155264-46-2)
- 2H-1,4-benzoxazine, 3,4-dihydro-3,6-dimethyl- (CAS 24033-49-6)
- 2H-1,4-Benzoxazine-2,3(4H)-dione (CAS 3597-63-5)
Recommended Standards
- N-Methyl-6-nitro-1,2-benzoxazole-3-carboxamide (CAS 400079-08-5)
- Mefatinib Impurity 4 (CAS 1012057-47-4)
- N-((Furan-2-carbonyl)oxy)-2-(methylamino)-2-oxoacetimidoyl cyanide (CAS 70792-03-9)
- 2-fluoro-5-methoxy-4-nitro-benzoic acid (CAS 1001345-80-7)
- 7-(trifluoromethoxy)quinolin-4-amine hydrochloride (CAS 1171441-04-5)
- 5-Thiazolecarboxylicacid, 4,5-dihydro-2-methyl-4-oxo-, ethyl ester 89776-82-9 ACMC-1CUO1 (CAS 89776-82-9)
- 3'-Phenyl-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidine]-2,4'-dione (CAS 79962-56-4)
- (3R)-3-amino-5-(methylthio)pentanoic acid;hydrochloride (3R)-3-amino-5-(methylthio)valeric acid;hydrochloride (3R)-3-amino-5-methylsulfanyl-pentanoic acid;hydrochloride (3R)-3-amino-5-methylsulfanylpentanoic acid;hydrochloride (3R)-3-azanyl-5-methylsulfanyl-pentanoic acid;hydrochloride 336182-07-1 D-beta-homomethionine-HCl (CAS 336182-07-1)
- 3-(4-Boronophenyl)propanoic acid (CAS 166316-48-9)
- 4-(Chloromethyl)-1-isopropyl-1H-pyrazole hydrochloride (CAS 1401425-39-5)
- 2-Pyrrolidinone, 1-ethenyl-, polymer with 1-butene (CAS 26160-96-3)
- 2-(5-Propoxy-1H-indol-3-yl)acetic acid (CAS 1270002-51-1)
- N-Methyl-N-(4-methyloxazol-2-yl)acetamide (CAS 57067-91-1)
- Allo-Thr5-Tirzepatide (CAS CATO-CPTD788934)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com