2-(3',4'-Difluoro-[1,1'-biphenyl]-2-yl)aceticacid CAS 886363-33-3

Purity 97%+In StockPharmaceutical Standards
CAS No.886363-33-3
Molecular FormulaC14H10F2O2
Molecular Weight248.22 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-(3',4'-Difluoro-[1,1'-biphenyl]-2-yl)aceticacid CAS 886363-33-3 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 248.22 g/mol gives 2-(3',4'-Difluoro-[1,1'-biphenyl]-2-yl)aceticacid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

2-(3',4'-Difluoro-[1,1'-biphenyl]-2-yl)aceticacid (CAS 886363-33-3), molecular formula C14H10F2O2 and molecular weight 248.22 g/mol, is a CATO reference standard with documented purity and traceability.

2-(3',4'-Difluoro-[1,1'-biphenyl]-2-yl)aceticacid (C14H10F2O2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, a polycyclic aromatic system. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 2-(3',4'-Difluoro-[1,1'-biphenyl]-2-yl)aceticacid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC14H10F2O2
Molecular Weight248.22 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)9.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1987
Halogen ContentF-containing

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