3-(3,4-Dichlorophenyl)tetrahydro-2H-pyran-2-one CAS 886363-68-4
| CAS No. | 886363-68-4 |
| Molecular Formula | C11H10Cl2O2 |
| Molecular Weight | 245.10 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 3-(3,4-Dichlorophenyl)tetrahydro-2H-pyran-2-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
3-(3,4-Dichlorophenyl)tetrahydro-2H-pyran-2-one (CAS 886363-68-4), molecular formula C11H10Cl2O2 and molecular weight 245.10 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 3-(3,4-Dichlorophenyl)tetrahydro-2H-pyran-2-one (C11H10Cl2O2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C11H10Cl2O2 |
| Molecular Weight | 245.10 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
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Recommended Standards
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- 2-Iodo-6-methoxy-4-(trifluoromethyl)pyridine (CAS 1805027-39-7)
- N-allyl-4-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-1H-pyrazole-1-carbothioamide (CAS 306976-64-7)
- rac Bendroflumethiazide (CAS 73-48-3)
- (4-Chloro-2-(1H-pyrazol-1-yl)phenyl)boronic acid (CAS 2225155-80-4)
- 2-Methylthieno[2,3-D]Pyrimidin-4-Amine (CAS 60703-75-5)
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