(5-Chloropyrazolo[1,5-a]pyridin-2-yl)methanamine CAS 886364-32-5
| CAS No. | 886364-32-5 |
| Molecular Formula | C8H8ClN3 |
| Molecular Weight | 181.62 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
(5-Chloropyrazolo[1,5-a]pyridin-2-yl)methanamine (CAS 886364-32-5), molecular formula C8H8ClN3 and molecular weight 181.62 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of (5-Chloropyrazolo[1,5-a]pyridin-2-yl)methanamine (C8H8ClN3) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), (5-Chloropyrazolo[1,5-a]pyridin-2-yl)methanamine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H8ClN3 |
| Molecular Weight | 181.62 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloropyrazolo Standards
- 5-Chloropyrazolo[1,5-a]pyrimidine-3-carbaldehyde (CAS 1256162-94-3)
- 7-Chloropyrazolo[1,5-a]pyrimidine-5-carbaldehyde (CAS 1346569-73-0)
- (5-Chloropyrazolo[1,5-a]pyrimidin-3-yl)methanamine (CAS 1263059-89-7)
- {3-chloropyrazolo[1,5-a]pyridin-5-yl}methanol (CAS 2765597-78-0)
- 5-Chloropyrazolo[1,5-a]pyridine-3-carbaldehyde (CAS 1101120-49-3)
- (5-Chloropyrazolo[1,5-a]pyrimidin-2-yl)methanol (CAS 1263059-09-1)
- (5-Chloropyrazolo[1,5-a]pyrimidin-3-yl)methanol (CAS 1263061-51-3)
- (4-Chloropyrazolo[1,5-a]pyrazin-2-yl)methanol (CAS 2821786-58-5)
Recommended Standards
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- (4-Chloro-2-pyridinyl)cyclopropyl-methanone (CAS 881204-94-0)
- (6-Chloroimidazo[1,2-a]pyridin-2-yl)methanamine (CAS 379726-34-8)
- 2,3,5-Trimethylfuran (CAS 10504-04-8)
- Methyl 4-chloro-6-methylpyridazine-3-carboxylate (CAS 2407962-27-8)
- 2-Amino-6-(4-chlorophenyl)-3,4,5,6-tetrahydropyrimidin-4-one (CAS 1072069-65-8)
- 6-Amino-4-chloro-5-(difluoromethyl)pyridine-2-sulfonamide (CAS 1805930-60-2)
- (R)-Propionyl Carnitine Chloride (CAS 119793-66-7)
- (1R,3R)-3-fluorocyclopentan-1-amine (CAS 1932124-81-6)
- Tert-butyl 5-(aminomethyl)spiro[indoline-3,3'-piperidine]-1'-carboxylate (CAS 1373028-54-6)
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- 7-(Morpholin-4-yl)quinazolin-4(3H)-one (CAS 1265848-98-3)
- Liraglutide Impurity 22 (CAS 536721-25-2)
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