1-(4-tert-butylphenyl)-2,2,2-trifluoroethan-1-amine CAS 886369-21-7
| CAS No. | 886369-21-7 |
| Molecular Formula | C12H16F3N |
| Molecular Weight | 231.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-(4-tert-butylphenyl)-2,2,2-trifluoroethan-1-amine.
1-(4-tert-butylphenyl)-2,2,2-trifluoroethan-1-amine (CAS 886369-21-7), molecular formula C12H16F3N and molecular weight 231.26 g/mol, is a CATO reference standard with documented purity and traceability.
1-(4-tert-butylphenyl)-2,2,2-trifluoroethan-1-amine (C12H16F3N) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H16F3N |
| Molecular Weight | 231.26 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related tert Standards
- (R)-1-(4-Butylphenyl)-2,2,2-trifluoroethan-1-amine (CAS 1213699-26-3)
- 1-(4-Butylphenyl)-2,2,2-trifluoroethan-1-amine (CAS 886368-50-9)
- 1-(4-tert-Butylphenyl)pyrrolidine-2,5-dione (CAS 98604-38-7)
- 4-(4-tert-Butylphenyl)-3-methyl-4,5-dihydro-1H-1,2,4-triazol-5-one (CAS 860612-43-7)
- 1-(4-tert-butylphenyl)piperidin-4-one (CAS 1019341-74-2)
- 4-(4-tert-butylphenyl)cyclohexan-1-amine (CAS 1369011-12-0)
- 2-[(4-tert-butylphenyl)methyl]-2-methylpyrrolidine (CAS 1542926-57-7)
- 1-(4-Butylphenyl)-3-methyl-1H-pyrazol-5(4H)-one (CAS 107430-32-0)
Recommended Standards
- 2,2,2-Trifluoro-1-(2,3,4,5-tetramethylphenyl)ethan-1-amine (CAS 886371-42-2)
- (R)-1-(4-(trifluoromethyl)phenyl)pentan-1-amine (CAS 869318-97-8)
- 2-Azabicyclo[2.1.1]hexane-2-carboxylic acid, 4-fluoro-3-(hydroxymethyl)-, 1,1-dimethylethyl ester (CAS 2927440-71-7)
- (2-Methylpropyl)({[4-(trifluoromethyl)phenyl]methyl})amine (CAS 637359-15-0)
- 5-Cyclopropaneamidothiophene-2-carboxylic acid (CAS 923244-16-0)
- 1-Cyclobutyl-3,5-bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole (CAS 2377610-66-5)
- 4-Ethoxy-N-isopentylaniline (CAS 1019490-32-4)
- 2-(2-Bromo-6-ethoxy-4-formylphenoxy)-N-(m-tolyl)acetamide (CAS 579523-41-4)
- N-[(4-Chlorobenzyl)oxy]-N-(3-cyano-4-methoxy-2-pyridinyl)iminoformamide (CAS 339102-41-9)
- 2-Amino-3-iodo-5-(trifluoromethyl)benzonitrile (CAS 1221792-71-7)
- 5-Ethyl-6-methyl-4-(p-tolyl)-3,4-dihydropyrimidin-2(1H)-one (CAS 728004-12-4)
- 10-(4-Fluorophenyl)-9,10-dihydroacridine (CAS 366015-67-0)
- 6-(ferrocenyl)hexanethiol (CAS 134029-92-8)
- (2S)-2-amino-4-(hydroxymethylphosphinyl)butanoyl-L-alanyl-L-alanine (2S)-2-amino-4-[hydroxy(methyl)phosphinoyl]butyryl-L-alanyl-L-alanine 2-Amino-4-(methylphosphino)butyrylalanylalanine 35597-43-4 Antibiotic SF 1293 Bialaphos CHEBI:3088 L-phosphinothricyl-L-alanyl-L-alanine N-{(2S)-2-amino-4-[hydroxy(methyl)phosphoryl]butanoyl}-L-alanyl-L-alanine PTT Phosphinothricylalanylalanine bilanafos gamma-(Hydroxymethylphosphinyl)-L-alpha-aminobutyryl-L-alanyl-L-alanine phosphinothricin tripeptide (CAS 35597-43-4)
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