2-Bromo-4-(pyridin-2-yl)thiazole CAS 886370-89-4
| CAS No. | 886370-89-4 |
| Molecular Formula | C8H5BrN2S |
| Molecular Weight | 241.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-Bromo-4-(pyridin-2-yl)thiazole is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
2-Bromo-4-(pyridin-2-yl)thiazole (CAS 886370-89-4), molecular formula C8H5BrN2S and molecular weight 241.11 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-Bromo-4-(pyridin-2-yl)thiazole (C8H5BrN2S) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-Bromo-4-(pyridin-2-yl)thiazole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H5BrN2S |
| Molecular Weight | 241.11 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Bromo Standards
- 5-bromo-3-phenyl-1,2,4-thiadiazole (CAS 101494-82-0)
- 3-Bromo-5-phenyl-1,2,4-thiadiazole (CAS 101495-43-6)
- 2-(4-Bromo-1,3-thiazol-2-yl)pyridine (CAS 1142195-09-2)
- 4-(4-Bromo-1,3-thiazol-2-yl)pyridine (CAS 1142195-11-6)
- 5-Bromo-2-(1,3-thiazol-4-yl)pyridine (CAS 1159820-13-9)
- 3-Bromo-4-phenyl-1,2,5-thiadiazole (CAS 151133-39-0)
- 2-Bromo-4-(pyridin-3-yl)thiazole (CAS 886370-95-2)
- 2-Bromo-4-(pyridin-4-yl)thiazole (CAS 886371-01-3)
Recommended Standards
- 2,5-Bis(3-bromophenyl)-1,3,4-oxadiazole (CAS 84832-73-5)
- 2-(Perfluoroethyl)isonicotinic acid (CAS 2090610-39-0)
- 1-Nitro-4-(perfluoroethyl)benzene (CAS 60979-14-8)
- 2-Bromo-5-phenyl-1,3,4-thiadiazole, 97% (CAS 53645-95-7)
- 1-Cyclopropyl-N-(piperidin-3-yl)methanesulfonamide (CAS 1483299-29-1)
- (4,5-Dimethyl-1h-imidazol-2-ylmethyl)-methyl-amine (CAS 193534-59-7)
- 2-(3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)thiazole (CAS 1314390-00-5)
- 5-chloro-4-(1-methyl-1H-pyrazol-5-yl)thiophene-2-carboxylic acid (CAS 1047630-55-6)
- 4-Cyano-2-(difluoromethyl)-3-nitropyridine-5-carboxaldehyde (CAS 1804421-98-4)
- Ethyl 5,6-dimethylpyrazine-2-carboxylate (CAS 62124-80-5)
- Diethyl ((4-nitrophenyl)sulfonyl)phosphoramidate (CAS 100133-08-2)
- S-ethyl hexanethioate (CAS 2450-12-6)
- 3-(Difluoromethyl)pyridine-4-carboxylic acid (CAS 1211541-32-0)
- D-Ala18-Tirzepatide (CAS CATO-CPTD788916)
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