3-(Difluoromethyl)-5-(propylthio)-4h-1,2,4-triazol-4-amine CAS 886496-00-0
| CAS No. | 886496-00-0 |
| Molecular Formula | C6H10F2N4S |
| Molecular Weight | 208.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
3-(Difluoromethyl)-5-(propylthio)-4h-1,2,4-triazol-4-amine (CAS 886496-00-0), molecular formula C6H10F2N4S and molecular weight 208.23 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 3-(Difluoromethyl)-5-(propylthio)-4h-1,2,4-triazol-4-amine (C6H10F2N4S) is characterized by a nitrile group, sulfur-containing functionality, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H10F2N4S |
| Molecular Weight | 208.23 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
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Recommended Standards
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- 436099-79-5 5-Diethylaminomethyl-furan-2-carboxylic acid 5-[(diethylamino)methyl]-2-furoic acid 5-diethylaminomethylfuran-2-carboxylic acid (CAS 436099-79-5)
- 3-Iodo-6-methyl-1H-pyrrolo[2,3-b]pyridine (CAS 1000340-29-3)
- Niraparib Tosylate Monohydrate (CAS 1613220-15-7)
- 3-Methyl-1-naphthol (CAS 13615-40-2)
- Methyl 1-methyl-3-(((methylsulfonyl)oxy)methyl)-1H-pyrazole-5-carboxylate (CAS 2460255-85-8)
- 1-(Phenylsulfonyl)-4-(1-piperazinyl)-1H-indole (CAS 412049-71-9)
- 1-[4-(3,4-Dimethoxyphenyl)-1,3-thiazol-2-yl]-3-methyl-1H-pyrazol-5-amine (CAS 1171834-04-0)
- 3-Benzoylcoumarin (CAS 1846-74-8)
- (4-((3-Chlorophenyl)carbamoyl)-3-fluorophenyl)boronic acid (CAS 2096331-72-3)
- Semaglutide impurity 95 (CAS CATO-C4X-222695)
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