3’-Chloro-5’-(trifluoromethyl)acetophenone CAS 886497-11-6
| CAS No. | 886497-11-6 |
| Molecular Formula | C9H6ClF3O |
| Molecular Weight | 222.59 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3’-Chloro-5’-(trifluoromethyl)acetophenone.
3’-Chloro-5’-(trifluoromethyl)acetophenone (CAS 886497-11-6), molecular formula C9H6ClF3O and molecular weight 222.59 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 3’-Chloro-5’-(trifluoromethyl)acetophenone (C9H6ClF3O) is characterized by a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 3’-Chloro-5’-(trifluoromethyl)acetophenone meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H6ClF3O |
| Molecular Weight | 222.59 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- 4-Chloro-2-(trifluoromethyl)-6,7-dihydro-5H-cyclopenta[d]pyrimidine (CAS 1023812-01-2)
- 1-(5-Chloro-2-(trifluoromethyl)phenyl)ethan-1-one (CAS 1214362-82-9)
- 1-(3-Chloro-2-methylphenyl)-2,2,2-trifluoroethan-1-one (CAS 1256467-21-6)
- 1-(5-Chloro-2-methylphenyl)-2,2,2-trifluoroethan-1-one (CAS 1256467-25-0)
- 4-Chloro-6-(trifluoromethyl)-2,3-dihydro-1H-pyrrolo[3,2-c]pyridine (CAS 1260666-44-1)
- 1-[3-chloro-4-(trifluoromethyl)phenyl]ethan-1-one (CAS 129322-80-1)
- 2’-Chloro-4’-(trifluoromethyl)acetophenone (CAS 129322-81-2)
- 1-(2-Chloro-3-(trifluoromethyl)phenyl)ethan-1-one (CAS 129322-82-3)
Recommended Standards
- 3,5-Dimethyl-2,4,6-trifluorobenzoyl chloride (CAS 886762-25-0)
- 3-Chloro-4-(trifluoromethyl)-6,7-dihydro-5H-cyclopenta[c]pyridazine (CAS 939758-08-4)
- 3-(Trifluoromethyl)phenylacetyl chloride (CAS 2003-14-7)
- 3-Chloro-6-cyclopropyl-4-(trifluoromethyl)pyridazine (CAS 929971-87-9)
- 2-(4-Chlorophenyl)-3,6,8-trimethylquinoline-4-carboxylic acid (CAS 895923-44-1)
- N1-(2-methylpyrimidin-4-yl)propane-1,3-diamine (CAS 1310120-38-7)
- Methiocarb Sulfone (CAS 2179-25-1)
- 4-Chloro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-d]pyrimidine (CAS 1830311-70-0)
- (3-(Trifluoromethyl)isoxazol-5-yl)methanol (CAS 93498-41-0)
- 1,4-Bis[(trimethylsilyl)ethynyl]benzene (CAS 17938-13-5)
- 5-amino-2-fluoro-4-methyl-N-phenylbenzene-1-sulfonamide (CAS 1409737-58-1)
- (3,4-Dichlorophenyl)(methyl)sulfane (CAS 17733-23-2)
- 3-Hydroxy-[1,1'-biphenyl]-4,4'-dicarboxylic acid (CAS 861600-11-5)
- Glucagon receptor antagonist I (CAS 438618-32-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com