3-Fluoro-4-(trifluoromethoxy)benzoyl chloride CAS 886499-09-8

Purity 97%+In StockPharmaceutical Standards
CAS No.886499-09-8
Molecular FormulaC8H3ClF4O2
Molecular Weight242.55 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

3-Fluoro-4-(trifluoromethoxy)benzoyl chloride CAS 886499-09-8 chemical structure

Description

The occurrence of 3-Fluoro-4-(trifluoromethoxy)benzoyl chloride is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

3-Fluoro-4-(trifluoromethoxy)benzoyl chloride (CAS 886499-09-8), molecular formula C8H3ClF4O2 and molecular weight 242.55 g/mol, is a CATO reference standard with documented purity and traceability.

3-Fluoro-4-(trifluoromethoxy)benzoyl chloride (C8H3ClF4O2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 3-Fluoro-4-(trifluoromethoxy)benzoyl chloride under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC8H3ClF4O2
Molecular Weight242.55 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at room temperature, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1987
Halogen ContentF/Cl-containing

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