4-((6,8-Dichloroquinazolin-4-yl)amino)butanoic acid CAS 886499-14-5
| CAS No. | 886499-14-5 |
| Molecular Formula | C12H11Cl2N3O2 |
| Molecular Weight | 300.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 4-((6,8-Dichloroquinazolin-4-yl)amino)butanoic acid (C12H11Cl2N3O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies 4-((6,8-Dichloroquinazolin-4-yl)amino)butanoic acid (CAS 886499-14-5), a certified reference material (molecular formula C12H11Cl2N3O2, MW 300.14 g/mol) for analytical method development and quality control.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H11Cl2N3O2 |
| Molecular Weight | 300.14 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Dichloroquinazolin Standards
- 2-((6,8-Dichloroquinazolin-4-yl)amino)propanoic acid (CAS 1008068-82-3)
- 4-(4,6-Dichloroquinazolin-2-yl)morpholine (CAS 60973-44-6)
- 2-((6,8-Dichloroquinazolin-4-yl)amino)acetic acid (CAS 886499-19-0)
- 2-(4,6-Dichloroquinazolin-2-yl)acetonitrile (CAS 258832-75-6)
- 2,5-dichloroquinazolin-4-ol (CAS 1107694-73-4)
- 4,7-dichloroquinazolin-2-amine (CAS 1378873-33-6)
- 4,5-dichloroquinazolin-2-amine (CAS 1379308-14-1)
- 6,7-dichloroquinazolin-2-amine (CAS 18672-00-9)
Recommended Standards
- 3-Amino-3-(5-(3,4-dichlorophenyl)furan-2-yl)propanoic acid (CAS 773125-94-3)
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- 3-Amino-3-(5-(2,5-dichlorophenyl)furan-2-yl)propanoic acid (CAS 773125-95-4)
- 4-{[(3,5-dichlorophenyl)amino]methylidene}-3-(methoxymethyl)-4,5-dihydro-1H-pyrazol-5-one (CAS 240799-64-8)
- 4'-(1,3-Dioxolan-2-yl)[1,1'-biphenyl]-4-carbonitrile (CAS 400744-45-8)
- Pcb No. 82 (CAS 52663-62-4)
- 2-Nitrothieno[2,3-b]pyridin-3-amine (CAS 52505-49-4)
- 6-Formylindolo[3,2-β]carbazole (CAS 172922-91-7)
- Ethyl 3-bromo-1H-pyrrolo[3,2-c]pyridine-4-carboxylate (CAS 1167055-83-5)
- 3-Chloro-4-fluorotoluene (CAS 1513-25-3)
- 3-(3-Bromo-5-fluorophenyl)-2,2-dimethylpropan-1-ol (CAS 1516755-88-6)
- 6-Chloro-4-(difluoromethyl)pyridin-3-ol (CAS 1806759-87-4)
- Boc-L-His(Trt)-Aib-OH (CAS 2061897-68-3)
- Semaglutide Impurity 4 (CAS CATO-C4X-22264)
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