2-[4,6-Bis(2,2,2-trifluoroethoxy)pyrimidin-2-yl)methylthio]acetic acid CAS 886762-32-9
| CAS No. | 886762-32-9 |
| Molecular Formula | C11H10F6N2O4S |
| Molecular Weight | 380.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 2-[4,6-Bis(2,2,2-trifluoroethoxy)pyrimidin-2-yl)methylthio]acetic acid (C11H10F6N2O4S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO supplies 2-[4,6-Bis(2,2,2-trifluoroethoxy)pyrimidin-2-yl)methylthio]acetic acid (CAS 886762-32-9), a certified reference material (molecular formula C11H10F6N2O4S, MW 380.26 g/mol) for analytical method development and quality control.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H10F6N2O4S |
| Molecular Weight | 380.26 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Bis Standards
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- 2,6-Bis(2,2,2-trifluoroethoxy)-3-bromobenzonitrile (CAS 175204-13-4)
- 4,7-Bis(2,2,2-trifluoroethoxy)-1,10-phenanthroline (CAS 2007920-74-1)
- 4-Methyl-3-(2,2,2-trifluoroethoxy)-5H-pyrido[1’,2’:4,5][1,2,4]thiadiazino[2,3-a]benzimidazol-13-ium Chloride (CAS 111712-17-5)
- 2,5-Bis(2,2,2-trifluoroethoxy)benzenesulfonyl chloride (CAS 152457-95-9)
- 2-(((3-Methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl)methyl)thio)-1H-benzo[d]imidazol-5-ol (CAS 131926-96-0)
- 2-({[2,5-bis(2,2,2-trifluoroethoxy)phenyl]formamido}oxy)acetic acid (CAS 338394-91-5)
- 2-[4,6-Bis(2,2,2-trifluoroethoxy)pyrimidin-2-yl)methylthio]ethylamine (CAS 886762-30-7)
Recommended Standards
- 2-(2-(4-Bromophenoxy)acetyl)-N-phenylhydrazine-1-carbothioamide (CAS 406190-67-8)
- 5-Bromo-2-((2-(dimethylcarbamoyl)phenyl)thio)benzoic acid (CAS 222021-56-9)
- 2-({[(4-bromophenyl)carbamoyl](phenyl)methyl}sulfanyl)acetic acid (CAS 339098-39-4)
- 6-(3-Chloropropoxy)-2-(4-(3-chloropropoxy)phenyl)benzo[d]oxazole (CAS 1219925-75-3)
- 1,2-Diphenylpropan-2-amine (CAS 118910-28-4)
- 2-(2-Nitroethyl)benzamide (CAS 400085-95-2)
- (1R,2S,4R)-4-(Methoxycarbonyl)-2-methylcyclohexane-1-carboxylic acid (CAS 2222709-29-5)
- tert-Butyl 3-oxo-1,2,3,5-tetrahydrospiro[2-benzazepine-4,4'-piperidine]-1'-carboxylate (CAS 1160247-91-5)
- 1,4-Dihydroxybutan-2-one (CAS 140-86-3)
- 3-Epicabraleadiol (CAS 19942-04-2)
- 3-Amino-3-(3-fluorophenyl)propanoicacid hcl (CAS 193633-57-7)
- 1-(3,3,3-Trifluoropropyl)piperazine (CAS 399580-61-1)
- Brexpiprazole Impurity 68 (CAS CATO-C4X-113168)
- Tau Peptide (304-318) trifluoroacetate salt (CAS 330456-49-0)
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