Ethyl 2,2-difluoro-3-hydroxy-3-(pyridin-3-yl)propanoate CAS 887355-01-3
| CAS No. | 887355-01-3 |
| Molecular Formula | C10H11F2NO3 |
| Molecular Weight | 231.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Ethyl 2,2-difluoro-3-hydroxy-3-(pyridin-3-yl)propanoate.
Ethyl 2,2-difluoro-3-hydroxy-3-(pyridin-3-yl)propanoate (CAS 887355-01-3) is a high-purity analytical reference standard with the molecular formula C10H11F2NO3 and a molecular weight of 231.20 g/mol.
The molecular framework of Ethyl 2,2-difluoro-3-hydroxy-3-(pyridin-3-yl)propanoate (C10H11F2NO3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures Ethyl 2,2-difluoro-3-hydroxy-3-(pyridin-3-yl)propanoate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H11F2NO3 |
| Molecular Weight | 231.20 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
- methyl 1-nitronaphthalene-2-carboxylate (CAS 78508-71-1)
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- methyl 3-methoxy-5-(trifluoromethyl)thiophene-2-carboxylate (CAS 181063-89-8)
- 3-[(2-Bromoacetyl)amino]-N-isopropylbenzamide (CAS 1138442-79-1)
- 3-Ethoxy-5-chloromethylisothiazole (CAS 170953-78-3)
- 4-Amino-6,7-dihydro-5H-cyclopenta[d]pyrimidine (CAS 26979-06-6)
- 1-Ethyl-4,5-dimethoxy-2-vinylbenzene (CAS 856351-46-7)
- 5-Oxo-5-((2-(pyrrolidin-1-yl)phenyl)amino)pentanoic acid (CAS 436088-74-3)
- 6-Chloro-N-cyclohexylpyridine-3-sulfonamide (CAS 622800-46-8)
- 3-(4,5,6,7-Tetrahydro-1H-indazol-3-yl)propanoic acid (CAS 196100-86-4)
- Semaglutide impurity 86 (CAS CATO-C4X-222686)
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