6-Chloro-2-(4-iodophenyl)imidazo[1,2-a]pyridine CAS 887360-01-2
| CAS No. | 887360-01-2 |
| Molecular Formula | C13H8ClIN2 |
| Molecular Weight | 354.57 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
6-Chloro-2-(4-iodophenyl)imidazo[1,2-a]pyridine (CAS 887360-01-2) is a high-purity analytical reference standard with the molecular formula C13H8ClIN2 and a molecular weight of 354.57 g/mol.
6-Chloro-2-(4-iodophenyl)imidazo[1,2-a]pyridine (C13H8ClIN2) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine/iodine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), 6-Chloro-2-(4-iodophenyl)imidazo[1,2-a]pyridine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H8ClIN2 |
| Molecular Weight | 354.57 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl/I-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- N-(2-chloro-4-hydroxy-6-iodopyridin-3-yl)pivalamide (CAS 1305324-95-1)
- 6-Chloro-3-iodo-2-phenylimidazo[1,2-a]pyridine (CAS 1426142-97-3)
- (2-Chloro-3-iodo-pyridin-4-yl)-carbamic acid tert-butyl ester (CAS 234108-74-8)
- 3-Chloro-2-[2-(2,4-dichlorophenyl)ethyl]-5-(trifluoromethyl)pyridine (CAS 439110-91-5)
- (3-Chloro-5-(trifluoromethyl)pyridin-2-yl)(2,4-dichlorophenyl)methanone (CAS 339106-12-6)
- 2-Chloro-1-(2,5-dichlorobenzyl)-1H-indole-3-carboxylic acid (CAS 93548-94-8)
- 6-Chloro-2-((3,4-dichlorobenzyl)amino)quinazolin-4(1H)-one (CAS 61741-58-0)
- 6-Chloro-N-(2,4-dichlorophenyl)-2H-chromene-3-carboxamide (CAS 338761-06-1)
Recommended Standards
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- Orlistat Impurity 16 (CAS 68711-40-0)
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- tert-Butyl (5-chloro-3-iodopyridin-2-yl)carbamate (CAS 2092000-52-5)
- 2-(Difluoromethyl)-3-fluoro-5-nitro-4-(trifluoromethyl)pyridine (CAS 1806976-71-5)
- Methyl 2-ethoxybenzoate (CAS 3686-55-3)
- Methyl (3R,4S,5S)-4-((tert-butoxycarbonyl)amino)-3-hydroxy-5-methylheptanoate (CAS 141394-85-6)
- 5-((4-Bromophenyl)thio)-4-chloro-2-(3-chlorophenyl)pyridazin-3(2H)-one (CAS 320421-80-5)
- 1-(Furan-2-yl)-2,8,9-trioxa-5-aza-1-silabicyclo[3.3.3]undecane (CAS 68011-86-9)
- 5-(2-Bromophenyl)-1h-pyrazole-4-carboxylic acid (CAS 1152544-01-8)
- N-((3-methyl-2-oxo-2,3-dihydrobenzo[d]oxazol-5-yl)methyl)acetamide (CAS 1788672-83-2)
- 2-(Furan-2-yl)-2-(4-methylpiperidin-1-yl)ethan-1-amine (CAS 889939-80-4)
- Methyl 3,5-dihydroxyphenylacetate, 97% (CAS 4724-10-1)
- Acetyl tetrapeptide-3 (CAS 827306-88-7)
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