4,6-Difluoro-1,2-dihydro-3H-indazol-3-one CAS 887567-77-3
| CAS No. | 887567-77-3 |
| Molecular Formula | C7H4F2N2O |
| Molecular Weight | 170.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4,6-Difluoro-1,2-dihydro-3H-indazol-3-one (CAS 887567-77-3) is a high-purity analytical reference standard with the molecular formula C7H4F2N2O and a molecular weight of 170.12 g/mol.
Structurally, 4,6-Difluoro-1,2-dihydro-3H-indazol-3-one (C7H4F2N2O) contains an amide group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 170.12 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4,6-Difluoro-1,2-dihydro-3H-indazol-3-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H4F2N2O |
| Molecular Weight | 170.12 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Difluoro Standards
- 6,7-Difluoro-1H-indazol-3-ol (CAS 1000343-93-0)
- 4,5-Difluoro-1H-pyrrolo[2,3-b]pyridin-2(3H)-one (CAS 1190315-56-0)
- 4,6-Difluoro-1H-pyrrolo[2,3-b]pyridin-2(3H)-one (CAS 1190318-81-0)
- 4,6-Difluoro-1,3-dihydro-2H-benzo[d]imidazol-2-one (CAS 1221793-66-3)
- 4,6-Difluoro-1,3-benzoxazol-2-amine (CAS 1339452-03-7)
- 5,6-difluoro-1,3-dihydrobenzimidazol-2-one (CAS 176244-21-6)
- 5,7-Difluoro-1H-Benzimidazole 3-Oxide (CAS 191847-81-1)
- 6,7-difluoro-2,3-dihydro-1-benzofuran-3-one (CAS 1260013-24-8)
Recommended Standards
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