4-Amino-3,5-dichloro-2-(trifluoromethyl)benzonitrile CAS 888073-10-7
| CAS No. | 888073-10-7 |
| Molecular Formula | C8H3Cl2F3N2 |
| Molecular Weight | 255.02 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 255.02 g/mol gives 4-Amino-3,5-dichloro-2-(trifluoromethyl)benzonitrile distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 4-Amino-3,5-dichloro-2-(trifluoromethyl)benzonitrile (CAS 888073-10-7), a certified reference material (molecular formula C8H3Cl2F3N2, MW 255.02 g/mol) for analytical method development and quality control.
The molecular framework of 4-Amino-3,5-dichloro-2-(trifluoromethyl)benzonitrile (C8H3Cl2F3N2) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 4-Amino-3,5-dichloro-2-(trifluoromethyl)benzonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H3Cl2F3N2 |
| Molecular Weight | 255.02 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Amino Standards
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- 2-Amino-4-bromomethyl-3-(trifluoromethyl)pyridine (CAS 1227508-24-8)
- 3-Amino-4-bromomethyl-2-(trifluoromethyl)pyridine (CAS 1227576-97-7)
- 2-Amino-4-bromomethyl-5-(trifluoromethyl)pyridine (CAS 1227581-27-2)
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Recommended Standards
- 4,7-Dichloro-2-(trifluoromethyl)-1H-benzo[d]imidazole (CAS 4228-89-1)
- 5,6-Dichloro-2-(trifluoromethyl)-1H-benzo[d]imidazole (CAS 2338-25-2)
- 4,6-Dichloro-2-(trifluoromethyl)-1H-benzo[d]imidazole (CAS 4228-88-0)
- 5-Bromo-4-(difluoromethoxy)-6-methoxypyrimidine (CAS 2750605-72-0)
- 2-Methyl-2-(1,2,3,4-tetrahydroquinolin-6-yl)propanoic acid (CAS 1892385-50-0)
- (1-(5-Chloropyrimidin-2-yl)piperidin-4-yl)methanol (CAS 1261230-05-0)
- 7-Hydrazinyl-2,5-dimethyl-3-(p-tolyl)pyrazolo[1,5-a]pyrimidine (CAS 900895-76-3)
- Ribavirin (CAS 36791-04-5)
- 4-Amino-3-bromo-5-(difluoromethyl)picolinaldehyde (CAS 1804450-18-7)
- 2-(1-Methyl-1H-imidazol-2-yl)pyridine (CAS 77429-59-5)
- RS 56812 (CAS 143137-35-3)
- 2-(4-((N-Ethylacetamido)methyl)piperidin-1-yl)acetic acid (CAS 1353982-13-4)
- 6-tert-Butylindole-2,4-dicarboxylic Acid (CAS 1000341-47-8)
- Semaglutide impurity 289 (CAS CATO-C4X-2226289)
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