Pyrimidine-5-carbothioamide CAS 88891-75-2
| CAS No. | 88891-75-2 |
| Molecular Formula | C5H5N3S |
| Molecular Weight | 139.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Pyrimidine-5-carbothioamide.
CATO supplies Pyrimidine-5-carbothioamide (CAS 88891-75-2), a certified reference material (molecular formula C5H5N3S, MW 139.18 g/mol) for analytical method development and quality control.
Owing to a nitrile group, sulfur-containing functionality, Pyrimidine-5-carbothioamide is typically off-white to pale yellow liquid. Its solid-state physicochemical attributes — including a molecular weight of 139.18 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C5H5N3S |
| Molecular Weight | 139.18 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1982 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Pyrimidine Standards
- Pyrimidine-2-carbothioamide (CAS 4537-73-9)
- pyrimidine-4-carbothioamide (CAS 88891-74-1)
- Pyrimidine-2,4-diyldimethanol (CAS 4425-66-5)
- Pyrimidine-4,6-diyldimethanol (CAS 50345-29-4)
- 35231-57-3 Pyrimidine, 5-ethoxy-2-methyl- (9CI) (CAS 35231-57-3)
- Pyrimidine-2-carboxylic acid hydrazide (CAS 87362-28-5)
- Pyrimidine-5-carbohydrazide (CAS 40929-42-8)
- methyl pyrimidine-2-carboxylate (CAS 34253-03-7)
Recommended Standards
- (R)-2-Cyclohexyl-2-hydroxyacetonitrile (CAS 100007-62-3)
- 2-Azaspiro[4.4]Nonan-1-one (CAS 1004-51-9)
- Pyridazine-4-carbothioamide (CAS 39123-43-8)
- 1-(Piperidin-1-yl)prop-2-en-1-one (CAS 10043-37-5)
- 2-Amino-3-chloro-4-fluorobenzoic acid (CAS 1855799-43-7)
- N-(4-((2-phenyl-5-tosylpyrimidin-4-yl)oxy)phenyl)acetamide (CAS 478247-36-8)
- (R,E)-4-(3-Phosphonoallyl)piperazine-2-carboxylic acid (CAS 117414-74-1)
- (S)-16,26-Bis(diphenylphosphanyl)-3,13-dioxa-1,2(1,3)-dibenzenacyclotridecaphane (CAS 1225281-42-4)
- (4-Methoxyphenyl)(phenyl)methanol (CAS 720-44-5)
- 2-(3-(((5-Cyano-6-oxo-4-(thiophen-2-yl)-1,6-dihydropyrimidin-2-yl)thio)methyl)phenyl)acetic acid (CAS 1883602-21-8)
- (E)-3-((1H-Indol-3-yl)methylene)-5-((E)-3,4-dimethoxybenzylidene)-1-methylpiperidin-4-one (CAS 1370032-19-1)
- 2-[1-(1-methylcyclopropyl)sulfonylazetidin-3-ylidene]acetonitrile (CAS 1187594-27-9)
- tert-Butyl(4-(chloromethyl)phenoxy)dimethylsilane (CAS 138585-09-8)
- CGMP Dependent Kinase Inhibitor Peptide (CAS 82801-73-8)
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