2-Bromo-1,3-dimethoxy-10-methylacridin-9(10H)-one CAS 88901-75-1

Purity 97%+In StockPharmaceutical Standards
CAS No.88901-75-1
Molecular FormulaC16H14BrNO3
Molecular Weight348.19 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-Bromo-1,3-dimethoxy-10-methylacridin-9(10H)-one CAS 88901-75-1 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Bromo-1,3-dimethoxy-10-methylacridin-9(10H)-one.

2-Bromo-1,3-dimethoxy-10-methylacridin-9(10H)-one (CAS 88901-75-1) is a high-purity analytical reference standard with the molecular formula C16H14BrNO3 and a molecular weight of 348.19 g/mol.

Structurally, 2-Bromo-1,3-dimethoxy-10-methylacridin-9(10H)-one (C16H14BrNO3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. The molecule exhibits a degree of unsaturation (DBE) of 10.0, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 348.19 g/mol, it falls into the moderately-high-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC16H14BrNO3
Molecular Weight348.19 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)10.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1982
Halogen ContentBr-containing
Nitrogen Atoms1

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