5-Chloro-2-methoxypyridine-4-carboxylic acid CAS 88912-22-5
| CAS No. | 88912-22-5 |
| Molecular Formula | C7H6ClNO3 |
| Molecular Weight | 187.58 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 5-Chloro-2-methoxypyridine-4-carboxylic acid (CAS 88912-22-5), a certified reference material (molecular formula C7H6ClNO3, MW 187.58 g/mol) for analytical method development and quality control.
The molecular framework of 5-Chloro-2-methoxypyridine-4-carboxylic acid (C7H6ClNO3) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 5-Chloro-2-methoxypyridine-4-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H6ClNO3 |
| Molecular Weight | 187.58 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1982 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
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- N-(6-Chloro-3-oxo-2,3-dihydropyridazin-4-yl)acetamide (CAS 100367-79-1)
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Recommended Standards
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- 5-Amino-3-chloro-2-hydroxybenzoic acid (CAS 54669-97-5)
- 5-Chloro-2-nitroanisole (CAS 6627-53-8)
- 2-(4-(1H-Imidazol-1-yl)butoxy)benzaldehyde hydrochloride (CAS 1609409-37-1)
- 4-Butylbenzene-1,3-diamine (CAS 63921-07-3)
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- 3',4',5'-Trimethoxy-[1,1'-biphenyl]-4-carboxylic acid (CAS 203722-36-5)
- 6-Bromo-7-(3-((tert-butyldimethylsilyl)oxy)propyl)-5-(p-tolyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine (CAS 821794-85-8)
- 4-Methyl-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-5-amine (CAS 1349988-68-6)
- 5-(Phenylamino)-1H-pyrazole-3-carboxylic acid (CAS 142115-63-7)
- (S)-2,2-dimethyl-1-(thiophen-3-yl)propan-1-amine (CAS 1389368-22-2)
- Methyl 8-amino-5,6,7,8-tetrahydronaphthalene-2-carboxylate (CAS 501441-76-5)
- Tirzepatide Impurity 35 (CAS CATO-C4X-324035)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com