1-(1H-Pyrazolo[3,4-b]pyridin-3-yl)ethanone CAS 889451-31-4
| CAS No. | 889451-31-4 |
| Molecular Formula | C8H7N3O |
| Molecular Weight | 161.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
1-(1H-Pyrazolo[3,4-b]pyridin-3-yl)ethanone (CAS 889451-31-4), molecular formula C8H7N3O and molecular weight 161.16 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 1-(1H-Pyrazolo[3,4-b]pyridin-3-yl)ethanone (C8H7N3O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H7N3O |
| Molecular Weight | 161.16 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 3 |
Related H Standards
- Pyrazolo[1,5-a]pyridine-5-carboxamide (CAS 1101120-03-9)
- 1-(1H-Pyrazolo[4,3-b]pyridin-3-yl)ethanone (CAS 1211525-04-0)
- 1-(2H-pyrazolo[4,3-b]pyridin-6-yl)ethan-1-one (CAS 1256787-55-9)
- Pyrazolo[1,5-a]pyridine-7-carboxamide (CAS 1373223-82-5)
- 1-(1H-Pyrazolo[4,3-c]pyridin-3-yl)ethanone (CAS 1386462-21-0)
- 1-(1H-Pyrazolo[3,4-c]pyridin-3-yl)ethan-1-one (CAS 1386462-22-1)
- 1-(Pyrazolo[1,5-a]pyrazin-3-yl)ethan-1-one (CAS 1550998-45-2)
- 1-(1H-Pyrazolo[4,3-b]pyridin-5-yl)ethanone (CAS 1822632-18-7)
Recommended Standards
- 1-(1H-Imidazol-2-yl)pyridin-2(1H)-one (CAS 393561-61-0)
- 1-(1H-Pyrazolo[4,3-b]pyridin-1-yl)ethanone (CAS 52090-62-7)
- 1-(1H-Imidazo[4,5-b]pyridin-2-yl)ethanone (CAS 250651-53-7)
- 1-(1H-Pyrazolo[4,3-c]pyridin-1-yl)ethanone (CAS 633328-87-7)
- 7-Methoxy-2,5-dimethyl-1H-imidazo[4,5-b]pyridine (CAS 863877-93-4)
- Pent-3-ynenitrile (CAS 19754-82-6)
- 4-Aminopiperidine-4-carboxylic acid hydrobromide (CAS 76508-55-9)
- 2-Chloro-9-(2-chloroethyl)-9H-purine-6-carboxylic acid (CAS 98557-68-7)
- 1,2-Didodecanoyl-sn-glycero-3-phosphoethanolamine 1,2-Dilauroyl-sn-glycero-3-phosphoethanolamine 3-sn-Phosphatidylethanolamine, 1,2-dilauroyl 59752-57-7 DLPE Dilauroyl phosphatidylethanolamine Dodecanoic acid (1R)-1-[[[(2-aminoethoxy)hydroxyphosphinyl]oxy]methyl]-1,2-ethanediyl ester L-|A,|A-Dilauroyl-|A-cephalin PE(12:0/12:0) (CAS 59752-57-7)
- N-((5-Oxo-1-phenylpyrrolidin-3-yl)methyl)-2-phenoxyacetamide (CAS 955219-52-0)
- (3-Fluoro-4-methoxyphenyl)(piperazin-1-yl)methanone (CAS 1255784-34-9)
- 2-(Ethylthio)-6,7-dihydro-5H-cyclopenta[b]pyridine-3-carbonitrile (CAS 340813-18-5)
- 2'-Chloro-[1,1'-biphenyl]-3-carboxylicacid (CAS 168619-03-2)
- Peptide Impurity 05 (CAS 2322924-83-2)
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