Ethyl 6-bromo-4-hydroxy-2-methylquinoline-3-carboxylate CAS 88960-40-1

Purity 97%+In StockPharmaceutical Standards
CAS No.88960-40-1
Molecular FormulaC13H12BrNO3
Molecular Weight310.14 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

Ethyl 6-bromo-4-hydroxy-2-methylquinoline-3-carboxylate CAS 88960-40-1 chemical structure

Description

CATO supplies Ethyl 6-bromo-4-hydroxy-2-methylquinoline-3-carboxylate (CAS 88960-40-1), a certified reference material (molecular formula C13H12BrNO3, MW 310.14 g/mol) for analytical method development and quality control.

Ethyl 6-bromo-4-hydroxy-2-methylquinoline-3-carboxylate (C13H12BrNO3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC13H12BrNO3
Molecular Weight310.14 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1982
Halogen ContentBr-containing
Nitrogen Atoms1

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