5-(Trifluoromethyl)-1,3,4-thiadiazole-3(2H)-carboxamide CAS 88976-74-3

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-(Trifluoromethyl)-1,3,4-thiadiazole-3(2H)-carboxamide.

5-(Trifluoromethyl)-1,3,4-thiadiazole-3(2H)-carboxamide (CAS 88976-74-3) is a high-purity analytical reference standard with the molecular formula C4H4F3N3OS and a molecular weight of 199.15 g/mol.

The molecular framework of 5-(Trifluoromethyl)-1,3,4-thiadiazole-3(2H)-carboxamide (C4H4F3N3OS) is characterized by an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.

As a certified reference material (CRM), 5-(Trifluoromethyl)-1,3,4-thiadiazole-3(2H)-carboxamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Why CATO?

• ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
• 130,000+ catalog items in stock, COA supplied with every batch
• Worldwide shipping with full export documentation (HS code guidance available)
• Technical support: +86 18665070610 / Nicole.chen@cato-chem.com