4-Bromoisothiazole-5-carboxylic acid CAS 88982-81-4
| CAS No. | 88982-81-4 |
| Molecular Formula | C4H2BrNO2S |
| Molecular Weight | 208.03 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-Bromoisothiazole-5-carboxylic acid.
CATO supplies 4-Bromoisothiazole-5-carboxylic acid (CAS 88982-81-4), a certified reference material (molecular formula C4H2BrNO2S, MW 208.03 g/mol) for analytical method development and quality control.
Structurally, 4-Bromoisothiazole-5-carboxylic acid (C4H2BrNO2S) contains an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, bromine substitution. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 208.03 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-Bromoisothiazole-5-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C4H2BrNO2S |
| Molecular Weight | 208.03 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1982 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Bromoisothiazole Standards
- 5-Bromoisothiazole-4-carboxylic acid (CAS 1651166-54-9)
- 4-Bromoisothiazole-3-carboxylic Acid (CAS 4576-88-9)
- 5-Bromoisothiazole-3-carboxylic acid (CAS 4576-89-0)
- 4-Bromoisothiazole-3-carbaldehyde (CAS 88982-79-0)
- 4-Bromoisothiazole-5-carbaldehyde (CAS 5242-62-6)
- 3-Bromoisothiazole-4-carbonitrile (CAS 1268247-73-9)
- 4-Bromoisothiazole-3-carbonitrile (CAS 89089-06-5)
- Ethyl 4-bromoisothiazole-5-carboxylate (CAS 2168896-84-0)
Recommended Standards
- 4-bromo-2-nitro-thiophene (CAS 85598-49-8)
- 5-Bromothiazole-2-carboxylic acid (CAS 957346-62-2)
- 4-Bromo-1,3-thiazole-2-carboxylic acid (CAS 88982-82-5)
- 1-Iodohex-3-yne (CAS 102998-71-0)
- 4-Ethynyl-1-methyl-1H-indole (CAS 959918-24-2)
- 3-(Tetrahydrofuran-2-yl)propyl dodecanoate (CAS 5453-18-9)
- 3-Bromo-n-ethoxy-4-methoxybenzamide (CAS 949812-43-5)
- 2-Bromo-1-(2-fluorophenyl)propan-1-one (CAS 186036-09-9)
- Methyl 2-{[2-(2-pyridinyl)-6-(trifluoromethyl)-4-pyrimidinyl]oxy}benzenecarboxylate (CAS 338754-17-9)
- (Z)-4-(4-chlorobenzylidene)-2-phenyloxazol-5(4h)-one (CAS 57427-77-7)
- Formoterol impurity 115 (CAS CATO-C4X-1525115)
- 5-Isocyanato-2-methoxypyridine (CAS 918525-01-6)
- Rosuvastatin Impurity 48 (CAS CATO-C4X-116948)
- Semaglutide impurity 98 (CAS CATO-C4X-222698)
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