5-(3-Fluoro-4-((6-methoxy-7-(3-morpholinopropoxy)quinolin-4-yl)oxy)phenyl)-2-((4-fluorophenyl)amino)-3-methylpyrimidin-4(3H)-one CAS 890019-63-3
| CAS No. | 890019-63-3 |
| Molecular Formula | C34H33F2N5O5 |
| Molecular Weight | 629.65 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, 5-(3-Fluoro-4-((6-methoxy-7-(3-morpholinopropoxy)quinolin-4-yl)oxy)phenyl)-2-((4-fluorophenyl)amino)-3-methylpyrimidin-4(3H)-one is typically pale yellow to yellow amorphous powder. Its solid-state physicochemical attributes — including a molecular weight of 629.65 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
5-(3-Fluoro-4-((6-methoxy-7-(3-morpholinopropoxy)quinolin-4-yl)oxy)phenyl)-2-((4-fluorophenyl)amino)-3-methylpyrimidin-4(3H)-one (CAS 890019-63-3), molecular formula C34H33F2N5O5 and molecular weight 629.65 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 5-(3-Fluoro-4-((6-methoxy-7-(3-morpholinopropoxy)quinolin-4-yl)oxy)phenyl)-2-((4-fluorophenyl)amino)-3-methylpyrimidin-4(3H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C34H33F2N5O5 |
| Molecular Weight | 629.65 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 20.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 5 |
Related Fluoro Standards
- 2-((2-Fluoro-4-((2-fluoro-3-nitrobenzyl)sulfonyl)phenyl)thio)-5-methoxy-N-(5-methyl-1H-pyrazol-3-yl)-6-morpholinopyrimidin-4-amine (CAS 1798871-30-3)
- 5-Fluoro-4,7-bis(5-(trimethylstannyl)thiophen-2-yl)benzo[c][1,2,5]thiadiazole (CAS 1611002-56-2)
- 7-Fluoro-8-((triisopropylsilyl)ethynyl)-3-((triisopropylsilyl)oxy)naphthalen-1-yl trifluoromethanesulfonate (CAS 2791271-66-2)
- 9-Acetyl-7-[3-Fluoro-5-(3-Fluorooxan-2-ylOxy-4-Hydroxy-6-Methyloxan-2-Yl]Oxy-6,9,11-Trihydroxy-4-Methoxy-8,10-Dihydro-7H-Tetracene-5,12-Dione (CAS 141291-21-6)
- 5-Fluoro-N-(2-((S)-1-methylpyrrolidin-2-yl)ethyl)-3-oxo-6-((S)-3-(pyrazin-2-yl)pyrrolidin-1-yl)-3H-benzo[b]pyrido[3,2,1-kl]phenoxazine-2-carboxamide (CAS 783364-52-3)
- (1E)-4-({2-fluoro-[1,1'-biphenyl]-4-yl}oxy)-1-{[4-(triphenylmethyl)phenyl]amino}pent-1-en-3-one (CAS 477888-65-6)
- 4'-Fluoro-2,3,3',4,5,6-hexabromodiphenyl ether (CAS 863314-88-9)
- 2-(3-Fluoro-4-(methylsulfonamido)phenyl)-N-((2-(4-methylpiperidin-1-yl)-6-(trifluoromethyl)pyridin-3-yl)methyl)-2-(m-tolyl)acetamide (CAS 1072449-00-3)
Recommended Standards
- Acarbose EP Impurity H (CAS 196944-81-7)
- Dabigatran Impurity 111 (CAS CATO-C4X-1089111)
- (R)-Perfluorophenyl 2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-((4-methoxybenzyl)thio)propanoate (CAS 150372-68-2)
- Suc-Phe-Pro-Phe-pNA (CAS 75651-68-2)
- 1-[(benzylcarbamoyl)amino]cyclopentane-1-carboxylic acid (CAS 929974-95-8)
- methyl N-(2-aminoethyl)carbamate hydrochloride (CAS 29170-19-2)
- 2-Amino-2-(3-methyl-2-thienyl)acetic Acid (CAS 500718-18-3)
- Quinoline, 6-(1-methylpropyl)- (CAS 65442-31-1)
- 1-(Quinolin-2-ylmethyl)cyclohexanol (CAS 132148-33-5)
- 2-((4-Allyl-5-(thiophen-2-yl)-4H-1,2,4-triazol-3-yl)thio)-N-(4-(dimethylamino)phenyl)acetamide (CAS 577698-26-1)
- 4-(difluoromethoxy)-3-(trifluoromethyl)aniline (CAS 71791-37-2)
- 2-((4,6-Difluoro-1,3,5-triazin-2-yl)amino)benzenesulfonic acid (CAS 60379-39-7)
- 2-[(3,4-Dichlorophenyl)methoxy]-5-[(4-methoxyphenoxy)methyl]-1,3-thiazole (CAS 339105-02-1)
- Sperm Peptide P10G (H-2424.0001) (CAS 137353-73-2)
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