8-Bromo-5-chloro-2-(trifluoromethyl)-1,6-naphthyridine CAS 890301-89-0
| CAS No. | 890301-89-0 |
| Molecular Formula | C9H3BrClF3N2 |
| Molecular Weight | 311.49 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 8-Bromo-5-chloro-2-(trifluoromethyl)-1,6-naphthyridine.
8-Bromo-5-chloro-2-(trifluoromethyl)-1,6-naphthyridine (CAS 890301-89-0) is a high-purity analytical reference standard with the molecular formula C9H3BrClF3N2 and a molecular weight of 311.49 g/mol.
The molecular framework of 8-Bromo-5-chloro-2-(trifluoromethyl)-1,6-naphthyridine (C9H3BrClF3N2) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 8-Bromo-5-chloro-2-(trifluoromethyl)-1,6-naphthyridine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H3BrClF3N2 |
| Molecular Weight | 311.49 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Cl/Br-containing |
| Nitrogen Atoms | 2 |
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- Methyl 3-(5-Oxazolyl)benzoate (CAS 850375-14-3)
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- 5-Fluoro-2-(methylsulfonyl)pyrimidine (CAS 6090-38-6)
- 1,5-Bis((4-(tert-butyl)phenyl)thio)anthracene-9,10-dione (CAS 84674-66-8)
- 3-[(2-Chloro-4,6-dimethylphenoxy)methyl]-pyrrolidine hydrochloride (CAS 1220029-22-0)
- Semaglutide238 (CAS CATO-C4X-2226238)
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