5-(5-Chlorothiophen-2-yl)-1H-pyrazole-3-carboxylic acid CAS 890621-34-8
| CAS No. | 890621-34-8 |
| Molecular Formula | C8H5ClN2O2S |
| Molecular Weight | 228.66 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 228.66 g/mol gives 5-(5-Chlorothiophen-2-yl)-1H-pyrazole-3-carboxylic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
5-(5-Chlorothiophen-2-yl)-1H-pyrazole-3-carboxylic acid (CAS 890621-34-8) is a high-purity analytical reference standard with the molecular formula C8H5ClN2O2S and a molecular weight of 228.66 g/mol.
5-(5-Chlorothiophen-2-yl)-1H-pyrazole-3-carboxylic acid (C8H5ClN2O2S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 5-(5-Chlorothiophen-2-yl)-1H-pyrazole-3-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H5ClN2O2S |
| Molecular Weight | 228.66 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Chlorothiophen Standards
- 3-(5-chlorothiophen-2-yl)-1H-pyrazole-4-carboxylic acid (CAS 1155045-53-6)
- 1-(5-Chlorothiophen-2-yl)-3-cyclopropylpropane-1,3-dione (CAS 1267754-08-4)
- 5-(5-Chlorothiophen-2-yl)-4-ethyl-1,2-oxazol-3-amine (CAS 1414958-76-1)
- (5-Chlorothiophen-2-yl)(thiophen-2-yl)methanone (CAS 203588-07-2)
- 6-(5-Chlorothiophen-2-yl)pyrimidine-2(1H)-thione (CAS 866019-24-1)
- 1-(5-Chlorothiophen-2-yl)-N-(furan-2-ylmethyl)methanamine (CAS 1021141-30-9)
- N-((5-chlorothiophen-2-yl)methyl)-1-methyl-1H-pyrazol-4-amine (CAS 1153130-71-2)
- n-((5-Chlorothiophen-2-yl)methyl)-1-methyl-1h-pyrazol-3-amine (CAS 1183450-59-0)
Recommended Standards
- 5-(2-Methylthiazol-4-yl)isoxazole-3-carbonyl chloride (CAS 368869-89-0)
- 5-Chloro-2-methyl-6-nitrobenzothiazole (CAS 5264-77-7)
- 4-Chloro-2-methyl-5-nitrobenzo[d]thiazole (CAS 2411087-38-0)
- 5-Quinoxalinesulfonyl Chloride (CAS 844646-88-4)
- 3,3,3-Trifluoro-2-(6-fluoro-1h-indol-3-yl)propanoic acid (CAS 1993099-07-2)
- N2,N2-dimethyl-6-(1-(methylthio)ethyl)-1,3,5-triazine-2,4-diamine (CAS 1280973-68-3)
- 2-Fluoro-N-methyl-5-(trifluoromethyl)aniline (CAS 1261468-40-9)
- (3'-Methyl-[1,1'-biphenyl]-4-yl)boronic acid (CAS 501944-56-5)
- 2-Oxo-2-(4-phenylphenyl)acetic Acid (CAS 5449-21-8)
- Buserelin Impurity 12 (CAS CATO-C4X-221212)
- Tert-butyl 8-amino-2-azadispiro[3.1.3(6).1(4)]Decane-2-carboxylate (CAS 2167233-72-7)
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- 8-methyl-5H-pyridazino[4,5-b]indole-4-thiol (CAS 950094-55-0)
- (Pro3)-Gastric Inhibitory Polypeptide (human) trifluoroacetate salt (CAS 299898-52-5)
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